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AB183501

Anti-LYVE1 抗体 [EPR13067(2)]

Anti-LYVE1 antibody [EPR13067(2)]

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(4 Publications)

Rabbit Recombinant Monoclonal LYVE1 antibody. Suitable for WB and reacts with Human samples. Cited in 4 publications.

別名を表示する

CRSBP1, HAR, XLKD1, UNQ230/PRO263, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, LYVE-1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, Hyaluronic acid receptor, CRSBP-1

1 Images
Western blot - Anti-LYVE1 antibody [EPR13067(2)] (AB183501)
  • WB

Supplier Data

Western blot - Anti-LYVE1 antibody [EPR13067(2)] (AB183501)

All lanes:

Western blot - Anti-LYVE1 antibody [EPR13067(2)] (ab183501) at 1/5000 dilution

Lane 1:

Human tonsil lysate at 20 µg

Lane 2:

A549 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 35 kDa

Observed band size: 35 kDa

false

関連する標識済み抗体及び組成の異なる製品 (1)

  • Carrier free

    Anti-LYVE1 antibody [EPR13067(2)] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR13067(2)

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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代替製品

Primary Antibodies

AB10278

Anti-LYVE1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYVE1 antibody (AB10278)

  • 3
  • 5
Primary Antibodies

AB219556

Anti-LYVE1 antibody [EPR21857]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYVE1 antibody [EPR21857] (AB219556)

  • 4
  • 7
Primary Antibodies

AB33682

Anti-LYVE1 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYVE1 antibody (AB33682)

  • 4
  • 15
Primary Antibodies

AB218535

Anti-LYVE1 antibody [EPR21771]

20ul selling size|RabMAb|Recombinant

Flow Cytometry - Anti-LYVE1 antibody [EPR21771] (AB218535)

  • 1
  • 1
Primary Antibodies

AB232935

Anti-LYVE1 antibody [EPR21857] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYVE1 antibody [EPR21857] - BSA and Azide free (AB232935)

  • 5
  • 2
Primary Antibodies

AB230377

Anti-LYVE1 antibody [EPR21771] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry - Anti-LYVE1 antibody [EPR21771] - BSA and Azide free (AB230377)

  • 0
  • 0
Primary Antibodies

AB14917

Anti-LYVE1 antibody - BSA and Azide free

Immunocytochemistry - Anti-LYVE1 antibody - BSA and Azide free (AB14917)

  • 4
  • 37
Primary Antibodies

AB36993

Anti-LYVE1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYVE1 antibody (AB36993)

  • 4
  • 3

組合せ製品

Assay Kits

AB238263

Human LYVE1 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human LYVE1 ELISA Kit (AB238263)

  • 0
  • 0
Primary Antibodies

AB199359

Anti-PROX1 antibody [EPR19273]

RabMAb|Advanced Validation|Recombinant|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-PROX1 antibody [EPR19273] (AB199359)

  • 4
  • 7
Primary Antibodies

AB281583

Anti-CD31 antibody [RM1006]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [RM1006] (AB281583)

  • 5
  • 5
Primary Antibodies

AB138492

Anti-Collagen I antibody [EPR7785]

20ul selling size|BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Frozen sections) - Anti-Collagen I antibody [EPR7785] (AB138492)

  • 4
  • 37
Primary Antibodies

AB124964

Anti-alpha smooth muscle Actin antibody [EPR5368]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-alpha smooth muscle Actin antibody [EPR5368] (AB124964)

  • 5
  • 19
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Conditional Ambient
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The protein "LYVE1" also known as Lymphatic Vessel Endothelial Hyaluronan Receptor 1 has a molecular mass of about 60 kDa. This protein is located on the surface of lymphatic endothelial cells. Its expression occurs mainly within the lymphatic vessels serving as an important marker for identifying lymphatic endothelium. LYVE1 facilitates the transportation of hyaluronan an important glycosaminoglycan through lymphatic vessels playing a critical role in the maintenance of extracellular matrix and tissue fluid homeostasis.
Biological function summary

LYVE1 plays a role in lymphatic system regulation and immune cell trafficking. It forms part of a network that binds hyaluronan contributing to the regulation of cell migration and adhesion. This protein interacts with molecules like CD44 and other receptors which also participate in hyaluronan binding. LYVE1's function in maintaining the balance of hyaluronan within tissues is central affecting not only the lymphatic system but also immune responses.

Pathways

LYVE1 engages in both the hyaluronan metabolism and lymphangiogenesis pathways. Its interaction with CD44 plays a significant role in the transport and uptake of hyaluronan influencing cellular processes such as proliferation and motility. These interactions link LYVE1 to pathways controlling fluid balance and immune surveillance marking it as essential for maintaining healthy lymphatic and immune function.

LYVE1 shows a connection to lymphatic-related conditions such as lymphedema and cancer metastasis. Alterations or dysregulation of LYVE1 expression can affect lymphatic function potentially leading to the accumulation of interstitial fluid as seen in lymphedema. In cancer increased LYVE1 expression can relate to tumor metastasis where it functions alongside proteins like VEGFR-3 in promoting lymphatic vessel growth and facilitating cancer cell spread.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes (PubMed : 10037799). Binds to pericelluar hyaluronan matrices deposited on the surface of leukocytes and facilitates cell adhesion and migration through lymphatic endothelium (PubMed : 26823460).
See full target information LYVE1
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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Neural regeneration research 19:1772-1780 PubMed38103244

2023

High-frequency repetitive transcranial magnetic stimulation promotes neural stem cell proliferation after ischemic stroke.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Luo,Yuan Feng,Zhongqiu Hong,Mingyu Yin,Haiqing Zheng,Liying Zhang,Xiquan Hu

Cells 12: PubMed37681927

2023

Lymphatic Endothelial-to-Myofibroblast Transition: A Potential New Mechanism Underlying Skin Fibrosis in Systemic Sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Irene Rosa,Eloisa Romano,Bianca Saveria Fioretto,Khadija El Aoufy,Silvia Bellando-Randone,Marco Matucci-Cerinic,Mirko Manetti

Brain sciences 13: PubMed36831830

2023

Double Blast Wave Primary Effect on Synaptic, Glymphatic, Myelin, Neuronal and Neurovascular Markers.

Applications

Unspecified application

Species

Unspecified reactive species

Diego Iacono,Erin K Murphy,Cheryl D Stimpson,Fabio Leonessa,Daniel P Perl

Acta neuropathologica communications 8:16 PubMed32059751

2020

Subdural haematomas drain into the extracranial lymphatic system through the meningeal lymphatic vessels.

Applications

Unspecified application

Species

Unspecified reactive species

Xuanhui Liu,Chuang Gao,Jiangyuan Yuan,Tangtang Xiang,Zhitao Gong,Hongliang Luo,Weiwei Jiang,Yiming Song,Jinhao Huang,Wei Quan,Dong Wang,Ye Tian,Xintong Ge,Ping Lei,Jianning Zhang,Rongcai Jiang
View all publications
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Abcam product promise

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