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AB317131

Anti-LRP4 antibody [HL2080]

Anti-LRP4 antibody [HL2080]

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Rabbit Monoclonal LRP4 antibody. Suitable for ICC/IF, WB and reacts with Rat, Human, Mouse samples. Immunogen corresponding to Recombinant Fragment Protein within Mouse Lrp4.

別名を表示する

Kiaa0816, Lrp4, Low-density lipoprotein receptor-related protein 4, LRP-4, LDLR dan

4 Images
Immunocytochemistry/ Immunofluorescence - Anti-LRP4 antibody [HL2080] (AB317131)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-LRP4 antibody [HL2080] (AB317131)

ab317131 detects LRP4 protein at cell membrane and nucleus by immunofluorescent analysis.
Sample : DIV9 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green : LRP4 stained by ab317131 diluted at 1 : 250.
Red : Tau a axon marker stained by Tau antibody diluted at 1 : 500.
Blue : Fluoroshield with DAPI.

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Whole cell extract (30 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

PC-3 whole cell extract at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

false

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Mouse tissue extract (50 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody and the signal was developed with Trident ECL plus-Enhanced.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

Mouse lung tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

true

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Mouse tissue extract (50 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

Mouse liver tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

HL2080

アイソタイプ

IgG

キャリアフリー

No

交差種

Human, Mouse, Rat

アプリケーション

ICC/IF, WB

applications

免疫原

Recombinant Fragment Protein within Mouse Lrp4.

Q8VI56

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/250", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
バッファー組成
pH: 7.4 Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. Plays an essential role in the process of digit differentiation (PubMed : 16517118).
See full target information Lrp4
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Abcam product promise

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