Anti-liver Arginase 抗体 (ab60176)
Key features and details
- Goat polyclonal to liver Arginase
- Suitable for: ICC, IHC-Fr, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-liver Arginase antibody
Liver Arginase 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to liver Arginase -
由来種
Goat -
アプリケーション
適用あり: ICC, IHC-Fr, WBmore details -
種交差性
交差種: Mouse, Rat -
免疫原
Synthetic peptide corresponding to Rat Liver Arginase aa 300-400 (C terminal).
Database link: NP_058830.2 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab60176の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC | (2) |
Use at an assay dependent concentration.
|
| IHC-Fr | (2) |
Use at an assay dependent concentration.
|
| WB | (1) |
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa).
A 1 hour primary incubation at room temperature is recommended for this product. |
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
|
IHC-Fr
Use at an assay dependent concentration. |
|
WB
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa). A 1 hour primary incubation at room temperature is recommended for this product. |
ターゲット情報
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パスウェイ
Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. -
関連疾患
Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia. -
配列類似性
Belongs to the arginase family. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 11846 Mouse
- Entrez Gene: 29221 Rat
- SwissProt: Q61176 Mouse
- SwissProt: P07824 Rat
- Unigene: 154144 Mouse
- Unigene: 9857 Rat
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別名
- A I antibody
- Al antibody
- ARG 1 antibody
see all
画像
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Western blot - Anti-liver Arginase antibody (ab60176)Lane 1 : Anti-liver Arginase antibody (ab60176) at 0.01 µg/ml
Lane 2 : Anti-liver Arginase antibody (ab60176) at 0.03 µg/ml
Lane 1 : Mouse liver lysate
Lane 2 : Rat liver lysate
Lysates/proteins at 35 µg per lane.
Predicted band size: 35 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (36)
ab60176 は 36 報の論文で使用されています。
- Li J et al. S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy. Nat Commun 13:1481 (2022). PubMed: 35304461
- Zhou J et al. Magnetic resonance imaging of tumor-associated-macrophages (TAMs) with a nanoparticle contrast agent. RSC Adv 12:7742-7756 (2022). PubMed: 35424752
- Sun SJ et al. Repeated intravenous administration of hiPSC-MSCs enhance the efficacy of cell-based therapy in tissue regeneration. Commun Biol 5:867 (2022). PubMed: 36008710
- Chen D et al. Interleukin-4 promotes microglial polarization toward a neuroprotective phenotype after retinal ischemia/reperfusion injury. Neural Regen Res 17:2755-2760 (2022). PubMed: 35662225
- Ma D et al. Inflammatory Microenvironment-Responsive Nanomaterials Promote Spinal Cord Injury Repair by Targeting IRF5. Adv Healthc Mater 11:e2201319 (2022). PubMed: 36165212