Anti-LDB2 抗体 (ab3627)
Key features and details
- Rabbit polyclonal to LDB2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-LDB2 antibody -
製品の詳細
Rabbit polyclonal to LDB2 -
由来種
Rabbit -
特異性
This affinity purified antibody is directed against mouse LDB2. A BLAST analysis was used to suggest reactivity with this protein from mouse, human, chimpanzee, dog, rat and chicken based on 100% homology for the immunogen sequence. Cross reactivity with LDB2 homologues from other sources has not been determined.
This antibody detects a single clean band representing LDB2 at 42kD in human kidney and mouse spleen.
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アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Chicken -
免疫原
Synthetic peptide:
SKESYHNSSITVDC
conjugated to KLH, corresponding to amino acids 107-120 of Human LDB2. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.01% Sodium azide
Constituents: 0.424% Tripotassium orthophosphate, 0.88% Sodium chloride -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
This affinity purified antibody is directed against mouse LDB2. The product was affinity purified from monospecific antiserum by immunoaffinity purification. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3627の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | ||
IHC-P |
特記事項 |
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WB: 1/500. Detects a band of approximately 42 kDa (predicted molecular weight: 42.7 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. -
配列類似性
Belongs to the LDB family. -
翻訳後修飾
Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 395631 Chicken
- Entrez Gene: 9079 Human
- Entrez Gene: 16826 Mouse
- Omim: 603450 Human
- SwissProt: Q9W676 Chicken
- SwissProt: O43679 Human
- SwissProt: O55203 Mouse
- Unigene: 714330 Human
see all -
別名
- Carboxyl terminal LIM domain binding protein 1 antibody
- Carboxyl terminal LIM domain protein 1 antibody
- Carboxyl-terminal LIM domain-binding protein 1 antibody
see all
画像
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Western blot using ab3627 at 1/500.
Lane 1: Human Kidney
Lane 2: Mouse SpleenLysates at 18
µ g per lane.
Secondary ab: Goat polyclonal to Rabbit IgG H&L (HRP) Pre-Adsorbed
ab7090 (1/5000).
Exposure time: 1 minute.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab3627 は 2 報の論文で使用されています。
- Cheng L et al. Generation and characterization of cardiac valve endothelial-like cells from human pluripotent stem cells. Commun Biol 4:1039 (2021). PubMed: 34489520
- Storbeck CJ et al. The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration. Mol Biol Cell 20:4174-82 (2009). ICC/IF ; Mouse . PubMed: 19675209