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AB308004

Anti-LCN1 抗体 [RP23040084]

Anti-LCN1 antibody [RP23040084]

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Rabbit Recombinant Multiclonal LCN1 antibody. Suitable for WB and reacts with Human samples.

別名を表示する

VEGP, LCN1, Lipocalin-1, Tear lipocalin, Tear prealbumin, von Ebner gland protein, Tlc, TP, VEG protein

1 Images
Western blot - Anti-LCN1 Antibody [RP23040084] (AB308004)
  • WB

Supplier Data

Western blot - Anti-LCN1 Antibody [RP23040084] (AB308004)

Western blot analysis of Lipocalin-1 in Jurkat whole cell extracts using ab308004 at a dilution of 2 µg/mL. Samples were detected using chemiluminescence (ECL). Results show a band at ~20kDa.

All lanes:

Western blot - Anti-LCN1 Antibody [RP23040084] (ab308004) at 2 µg/mL

All lanes:

Jurkat whole cell lysate

Predicted band size: 19 kDa

Observed band size: 20 kDa

true

Key facts

宿主種

Rabbit

クローン性

Multiclonal

クローン番号

RP23040084

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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組合せ製品

Assay Kits

AB313984

Human LCN1 ELISA Kit

Sandwich ELISA - Human LCN1 ELISA Kit (AB313984)

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Primary Antibodies

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Anti-MYH8 antibody

Western blot - Anti-MYH8 antibody (AB201316)

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Primary Antibodies

AB151749

Anti-MYL1 antibody [EPR9934(B)]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-MYL1 antibody [EPR9934(B)] (AB151749)

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Primary Antibodies

AB109418

Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)]

20ul selling size|RabMAb|Recombinant

Western blot - Anti-PI4 kinase beta/PI4KB antibody [EPR3758(2)] (AB109418)

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Primary Antibodies

AB181141

Anti-IGFBP1 antibody [EPR14472(B)]

RabMAb|Recombinant

Western blot - Anti-IGFBP1 antibody [EPR14472(B)] (AB181141)

  • 3
  • 1
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p></p>" } } }
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製品の詳細

What are recombinant multiclonals?
Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including:

  • - The sensitivity of polyclonal antibodies by recognising multiple epitopes
  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

View our range of recombinant multiclonal antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
バッファー組成
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

LCN1 also known as Lipocalin-1 or tear lipocalin is a secreted protein with a mass of approximately 21 kDa. It primarily localizes in human tears and other secretions including saliva. This protein belongs to the lipocalin family known for their small size and ability to bind hydrophobic molecules. Its key function includes transporting small lipophilic molecules such as fatty acids and retinoids contributing to ocular surface health.
Biological function summary

LCN1 plays an essential role in protecting the eye's surface. It binds and neutralizes bacteria-derived lipopolysaccharides which helps to control microbial growth on the eye surface. LCN1 may interact with other components present in tear film but it does not form a complex with them. The protein participates in transporting molecules across cell membranes and modulating the immune response at ocular and oral sites.

Pathways

LCN1 has a significant role in the defense mechanisms of the tear film. It engages in the immune response pathway helping to maintain homeostasis in the ocular surface microenvironment. Its binding capabilities are related to fatty acid transport pathways. LCN1 indirectly interacts with proteins related to lipid transport such as albumin due to its role in managing lipid interactions at epithelial surfaces.

LCN1 shows a connection to dry eye syndrome a condition resulting from insufficient tear production or quality leading to inflammation and damage to the eye surface. The protein also relates to Sjögren’s syndrome an autoimmune disorder affecting moisture-producing glands. These associations arise because LCN1's deficiency or dysfunction can contribute to the pathology observed in these disorders alongside proteins like lactoferrin which is also important in tear film stability and ocular health.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
See full target information LCN1
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