Anti-Kif2a 抗体 (ab3475)
Key features and details
- Rabbit polyclonal to Kif2a
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Kif2a antibody
Kif2a 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Kif2a -
由来種
Rabbit -
特異性
Detects Kinesin 2 (Kif2a) from mouse tissues. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat, Chicken, Cow, Human, Xenopus laevis, Orangutan -
免疫原
Synthetic peptide corresponding to Mouse Kif2a aa 1-11.
Sequence:MVTSLNEDNES
(Peptide available asab4992) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 99% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab3475の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 79 kDa.
This antibody detects a ~95 kDa protein representing KIF 2 from mouse brain homogenate. |
特記事項 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 79 kDa. This antibody detects a ~95 kDa protein representing KIF 2 from mouse brain homogenate. |
ターゲット情報
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機能
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity. -
配列類似性
Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
Contains 1 kinesin-motor domain. -
細胞内局在
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1. - Information by UniProt
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参照データベース
- Entrez Gene: 3796 Human
- Entrez Gene: 16563 Mouse
- Entrez Gene: 84391 Rat
- Entrez Gene: 379622 Xenopus laevis
- Omim: 602591 Human
- SwissProt: O00139 Human
- SwissProt: P28740 Mouse
- SwissProt: Q9WV63 Rat
see all -
別名
- CDCBM3 antibody
- HK2 antibody
- KIF2 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab3475 は 1 報の論文で使用されています。
- Patel M et al. Osteopontin and LDLR Are Upregulated in Hearts of Sudden Cardiac Death Victims With Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus. Front Cardiovasc Med 7:610282 (2020). PubMed: 33330671