Anti-KAT9 / Elp3 抗体 (ab113228)
Key features and details
- Rabbit polyclonal to KAT9 / Elp3
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-KAT9 / Elp3 antibody
KAT9 / Elp3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to KAT9 / Elp3 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cow, Zebrafish
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免疫原
Recombinant full length protein. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human Tonsil and Uterus tissues; NT2D1 whole cell lysate; HeLa cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 89% Tris glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113228の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 62 kDa.
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| IHC-P |
Use a concentration of 10 µg/ml.
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| ICC/IF |
1/100 - 1/200.
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| 特記事項 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 62 kDa. |
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IHC-P
Use a concentration of 10 µg/ml. |
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ICC/IF
1/100 - 1/200. |
ターゲット情報
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機能
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity. -
配列類似性
Belongs to the ELP3 family.
Contains 1 N-acetyltransferase domain. -
細胞内局在
Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 55140 Human
- Entrez Gene: 74195 Mouse
- Entrez Gene: 541509 Zebrafish
- Omim: 612722 Human
- SwissProt: Q9H9T3 Human
- SwissProt: Q9CZX0 Mouse
- SwissProt: Q5RIC0 Zebrafish
- Unigene: 491336 Human
see all -
別名
- DKFZp761L098 antibody
- Elongation protein 3 homolog (S. cerevisiae) antibody
- Elongation protein 3 homolog antibody
see all
画像
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Western blot - Anti-KAT9 / Elp3 antibody (ab113228)Anti-KAT9 / Elp3 antibody (ab113228) at 1/2000 dilution + NT2D1 whole cell lysate at 30 µg
Predicted band size: 62 kDa
7.5% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KAT9 / Elp3 antibody (ab113228)ab113228, at 10µg/ml, staining KAT9 / Elp3 in Formalin-fixed, Paraffin-embedded Human Tonsil tissue by Immunohistochemistry. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KAT9 / Elp3 antibody (ab113228)ab113228, at 10µg/ml, staining KAT9 / Elp3 in Formalin-fixed, Paraffin-embedded Human Uterus tissue by Immunohistochemistry. -
Immunocytochemistry/ Immunofluorescence - Anti-KAT9 / Elp3 antibody (ab113228)ab113228 at 1/100 dilution staining KAT9 / Elp3 in paraformaldehyde-fixed HeLa cells by Immunofluorescence. The lower image is merged with DNA probe.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab113228 は 1 報の論文で使用されています。
- Xu S et al. Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. Nat Commun 10:5492 (2019). PubMed: 31792210