Anti-Kallistatin/PI-4 抗体 [EPR15310] (ab187656)
![Western blot - Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656)](https://www.abcam.co.jp/ps/products/187/ab187656/Images/ab187656-220713-anti-kallistatin-pi-4-antibody-epr15310-western-blot.jpg "Western blot - Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR15310] to Kallistatin/PI-4
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-Kallistatin/PI-4 antibody [EPR15310]
Kallistatin/PI-4 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR15310] to Kallistatin/PI-4 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse
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免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Human plasma lysate.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS, 0.05% BSA -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR15310 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187656の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/2000. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
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| 特記事項 |
|---|
|
WB
1/1000 - 1/2000. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa). |
ターゲット情報
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機能
Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. -
組織特異性
Expressed by the liver and secreted in plasma. -
配列類似性
Belongs to the serpin family. -
翻訳後修飾
The N-terminus is blocked. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 5267 Human
- Omim: 147935 Human
- SwissProt: P29622 Human
- Unigene: 719893 Human
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別名
- KAIN_HUMAN antibody
- KAL antibody
- Kallikrein binding protein antibody
see all
画像
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Western blot - Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656)Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656) at 1/1000 dilution + Human plasma lysate at 20 µg
Secondary
Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution
Developed using the ECL technique.
Predicted band size: 49 kDa
Observed band size: 49 kDa -
![Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656)](https://www.abcam.co.jp/ps/products/187/ab187656/Images/ab187656-2-benefits-of-recombinant-antibodies.png)
Anti-Kallistatin/PI-4 antibody [EPR15310] (ab187656)
データシートおよび資料
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SDS download
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Datasheet download
Certificate of Compliance
参考文献 (2)
ab187656 は 2 報の論文で使用されています。
- Huang J et al. Kallistatin prevents ovarian hyperstimulation syndrome by regulating vascular leakage. J Cell Mol Med 26:4613-4623 (2022). PubMed: 35866203
- Liang W et al. Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling. Diabetes 71:747-761 (2022). PubMed: 35044447