Anti-Kallikrein 5 抗体 (ab7283)
Key features and details
- Rabbit polyclonal to Kallikrein 5
- Isotype: IgG
製品の概要
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製品名
Anti-Kallikrein 5 antibody
Kallikrein 5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Kallikrein 5 -
由来種
Rabbit -
免疫原
Synthetic peptide, corresponding to amino acids 280-293 of Human KLK5.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
ターゲット情報
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機能
May be involved in desquamation. -
組織特異性
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. -
配列類似性
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
細胞内局在
Secreted. - Information by UniProt
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別名
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (6)
ab7283 は 6 報の論文で使用されています。
- Somogyi O et al. New Data on the Features of Skin Barrier in Hidradenitis Suppurativa. Biomedicines 11:N/A (2023). PubMed: 36672635
- Kapitány A et al. Regional Differences in the Permeability Barrier of the Skin-Implications in Acantholytic Skin Diseases. Int J Mol Sci 22:N/A (2021). PubMed: 34638769
- Furio L et al. Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. J Exp Med 211:499-513 (2014). PubMed: 24534191
- Bonnart C et al. Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest 120:871-82 (2010). IHC-P ; Human . PubMed: 20179351
- Yanagi T et al. Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice. Am J Pathol 177:106-18 (2010). WB, IHC-P ; Mouse . PubMed: 20489143
- Di WL et al. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161:404-12 (2009). WB ; Human . PubMed: 19438860