Anti-Kallikrein 5 抗体 (ab28565)
Key features and details
- Rabbit polyclonal to Kallikrein 5
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
製品の概要
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製品名
Anti-Kallikrein 5 antibody
Kallikrein 5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Kallikrein 5 -
由来種
Rabbit -
特異性
This antibody reacts with Kallikrein 5, but does not react with the other Kallikreins (1-7 and 9-15). -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Synthetic peptide based on the Kallikrein loop area of human Kallikrein 5.
Immunogen の所有権に関して (Peptide available as ab41423.) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab28565の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/5000. Predicted molecular weight: 32 kDa. 1/1000 (when using colorimetric substrates such as BCIP/NBT)- 1/5000 (chemiluminescent substrates). Dilution optimised using Chromogenic detection.
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| 特記事項 |
|---|
|
WB
1/1000 - 1/5000. Predicted molecular weight: 32 kDa. 1/1000 (when using colorimetric substrates such as BCIP/NBT)- 1/5000 (chemiluminescent substrates). Dilution optimised using Chromogenic detection. |
ターゲット情報
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機能
May be involved in desquamation. -
組織特異性
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. -
配列類似性
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
細胞内局在
Secreted. - Information by UniProt
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別名
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
see all
画像
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Western blot - Anti-Kallikrein 5 antibody - Kallikrein loop (ab28565)All lanes : Anti-Kallikrein 5 antibody (ab28565) at 1/1000 dilution
Lane 1 : Kallikrein 5 at 0.05 µg
Lane 2 : Kallikrein 5 at 0.01 µg
Lane 3 : Kallikrein 5 at 0.001 µg
Predicted band size: 32 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab28565 は 5 報の論文で使用されています。
- Alves MG et al. Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma. Transl Oncol 14:100970 (2021). PubMed: 33260070
- Abuduhadeer X et al. Clinical significance of kallikrein 5 as a novel prognostic biomarker in gastric adenocarcinoma. J Clin Lab Anal 35:e23958 (2021). PubMed: 34510543
- Jiang R et al. Kallikrein-5 promotes cleavage of desmoglein-1 and loss of cell-cell cohesion in oral squamous cell carcinoma. J Biol Chem 286:9127-35 (2011). ICC/IF ; Human . PubMed: 21163944
- Ghosh S et al. Urinary-type plasminogen activator receptor/alpha 3 beta 1 integrin signaling, altered gene expression, and oral tumor progression. Mol Cancer Res 8:145-58 (2010). IHC-P ; Mouse . PubMed: 20145038
- Pettus JR et al. Multiple kallikrein (KLK 5, 7, 8, and 10) expression in squamous cell carcinoma of the oral cavity. Histol Histopathol 24:197-207 (2009). PubMed: 19085836