Anti-JOSD1 抗体 (ab118221)
Key features and details
- Rabbit polyclonal to JOSD1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-JOSD1 antibody -
製品の詳細
Rabbit polyclonal to JOSD1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant fragment corresponding to Human JOSD1 aa 44-188. (BC015026)
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ポジティブ･コントロール
- WB: A549 and HepG2 cell lysates. IHC: human prostate carcinoma tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab118221 is purified by a protein affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab118221の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
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| IHC-P |
1/100 - 1/500.
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa). |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Has low protease activity towards poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme. -
配列類似性
Contains 1 Josephin domain. - Information by UniProt
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参照データベース
- Entrez Gene: 9929 Human
- Entrez Gene: 74158 Mouse
- Entrez Gene: 315134 Rat
- SwissProt: Q15040 Human
- SwissProt: Q9DBJ6 Mouse
- SwissProt: Q5BJY4 Rat
- Unigene: 3094 Human
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別名
- dJ508I15.2 antibody
- JOS1_HUMAN antibody
- Josd1 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JOSD1 antibody (ab118221)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labeling JOSD1 with ab118221 at a dilution of 1/100.
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Western blot - Anti-JOSD1 antibody (ab118221)All lanes : Anti-JOSD1 antibody (ab118221) at 1/500 dilution
Lane 1 : HepG2 cell lysate
Lane 2 : A549 cell lysate
Predicted band size: 23 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab118221 は 1 報の論文で使用されています。
- Wu X et al. JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1. Cell Death Differ N/A:N/A (2019). PubMed: 31043700