Anti-ITIH2/SHAP 抗体 (ab118257)
Key features and details
- Rabbit polyclonal to ITIH2/SHAP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ITIH2/SHAP antibody
ITIH2/SHAP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ITIH2/SHAP -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant fragment corresponding to Human ITIH2/SHAP aa 124-321.
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ポジティブ･コントロール
- WB: Fetal brain lysate IHC-P: Fetal brain tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab118257の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa).
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| IHC-P |
1/100 - 1/500.
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa). |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. -
組織特異性
Plasma. -
配列類似性
Belongs to the ITIH family.
Contains 1 VIT domain.
Contains 1 VWFA domain. -
翻訳後修飾
Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
Phosphorylation sites are present in the extracelllular medium. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3698 Human
- Entrez Gene: 16425 Mouse
- Omim: 146640 Human
- SwissProt: P19823 Human
- SwissProt: Q61703 Mouse
- Unigene: 75285 Human
- Unigene: 182043 Mouse
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別名
- AI747202 antibody
- H2P antibody
- IGHEP2 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ITIH2/SHAP antibody (ab118257)Immunohistochemical analysis of formalin fixed paraffin embedded Human fetal brain tissue using ab118257 at 1/100
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Western blot - Anti-ITIH2/SHAP antibody (ab118257)Anti-ITIH2/SHAP antibody (ab118257) at 1/500 dilution + Human Fetal brain lysate
Predicted band size: 106 kDa
Observed band size: 106 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab118257 は 3 報の論文で使用されています。
- Heindel DW et al. Glycomic Analysis Reveals a Conserved Response to Bacterial Sepsis Induced by Different Bacterial Pathogens. ACS Infect Dis 8:1075-1085 (2022). PubMed: 35486714
- Martin J et al. Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-a-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation. J Biol Chem 291:13789-801 (2016). PubMed: 27143355
- He H et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . PubMed: 23878196