Anti-ITGA11 抗体 (ab114113)
Key features and details
- Goat polyclonal to ITGA11
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-ITGA11 antibody
ITGA11 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to ITGA11 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Rat
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免疫原
Synthetic peptide:
C-PTEEDLSHAPQRNH
, corresponding to C terminal amino acids 1047-1060 of Mouse ITGA11 (NP_795896.4). -
ポジティブ･コントロール
- Mouse skeletal muscle lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99.48% Tris buffered saline -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab114113 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab114113の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 133 kDa).
1 hour primary incubation is recommended for this product. |
| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 140 kDa (predicted molecular weight: 133 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Integrin alpha-11/beta-1 is a receptor for collagen. -
組織特異性
According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
発生段階
Strongly up-regulated in differentiating fetal muscle cells (in vitro). -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 319480 Mouse
- Entrez Gene: 315744 Rat
- SwissProt: P61622 Mouse
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別名
- integrin a11 antibody
- Integrin alpha 11 antibody
- Integrin alpha-11 antibody
see all
画像
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Western blot - Anti-ITGA11 antibody (ab114113)Anti-ITGA11 antibody (ab114113) at 1 µg/ml + Mouse skeletal muscle lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 133 kDa
Observed band size: 140 kDa why is the actual band size different from the predicted?
Primary incubation: 1 hour
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab114113 は 2 報の論文で使用されています。
- Marmotti A et al. Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells as a Potential Source for Cartilage and Bone Regeneration: AnIn VitroStudy. Stem Cells Int 2017:1732094 (2017). PubMed: 29358953
- Verma R et al. Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One 11:e0148906 (2016). PubMed: 26848974