Anti-Interferon gamma 抗体 [MD-1] (ab25014)
![Sandwich ELISA - Anti-Interferon gamma antibody [MD-1] (ab25014)](https://www.abcam.co.jp/ps/products/25/ab25014/Images/ab25014-35754-anti-interferon-gamma-antibody-md-1-sandwich-elisa.jpg "Sandwich ELISA - Anti-Interferon gamma antibody [MD-1] (ab25014)")
Key features and details
- Mouse monoclonal [MD-1] to Interferon gamma
- Suitable for: Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
製品の概要
-
製品名
Anti-Interferon gamma antibody [MD-1]
Interferon gamma 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MD-1] to Interferon gamma -
由来種
Mouse -
特異性
The antibody recognises IFN-gamma but does not react IFN-alpha and beta. -
アプリケーション
適用あり: Sandwich ELISAmore details -
種交差性
交差種: Human
非交差種: Mouse, Rat -
免疫原
Recombinant full length protein (Human)
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.05% Sodium azide
Constituents: PBS, 4.275% Trehalose -
Concentration information loading... -
精製度
Ion Exchange Chromatography -
ポリ/モノ
モノクローナル -
クローン名
MD-1 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Conjugation kits
-
Isotype control
-
Recombinant Protein
-
sELISA pair antibody
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25014の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Sandwich ELISA |
Use a concentration of 5 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Interferon gamma (ab25101).
For sandwich ELISA, use this antibody as Capture at 5µg/ml with ab25101 as Detection. |
| 特記事項 |
|---|
|
Sandwich ELISA
Use a concentration of 5 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Interferon gamma (ab25101). For sandwich ELISA, use this antibody as Capture at 5µg/ml with ab25101 as Detection. |
ターゲット情報
-
機能
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. -
組織特異性
Released primarily from activated T lymphocytes. -
関連疾患
In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. -
配列類似性
Belongs to the type II (or gamma) interferon family. -
翻訳後修飾
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 3458 Human
- Omim: 147570 Human
- SwissProt: P01579 Human
- Unigene: 856 Human
-
別名
- IF 1 antibody
- IFG antibody
- IFI antibody
see all
画像
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab25014 は 2 報の論文で使用されています。
- Chua KV et al. Octyl Gallate Induces Pancreatic Ductal Adenocarcinoma Cell Apoptosis and Suppresses Endothelial-Mesenchymal Transition-Promoted M2-Macrophages, HSP90a Secretion, and Tumor Growth. Cells 9:N/A (2019). PubMed: 31905895
- Aebischer J et al. Elevated levels of IFNγ and LIGHT in the spinal cord of patients with sporadic amyotrophic lateral sclerosis. Eur J Neurol 19:752-9, e45-6 (2012). PubMed: 22221541