Anti-Interferon alpha/beta receptor 1 (phospho S535 + S539) 抗体 (ab30571)
Key features and details
- Rabbit polyclonal to Interferon alpha/beta receptor 1 (phospho S535 + S539)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Interferon alpha/beta receptor 1 (phospho S535 + S539) antibody
Interferon alpha/beta receptor 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Interferon alpha/beta receptor 1 (phospho S535 + S539) -
由来種
Rabbit -
特異性
Specific for Interferon alpha/beta receptor 1 protein phosphorylated at Ser535,539 in Western blots of human brain extracts. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human Interferon alpha/beta receptor 1 (phospho S535 + S539).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.50
Constituents: 0.238% HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Prepared from rabbit serum by affinity purification via sequential chromatography on phospho-and dephosphopeptide affinity columns. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab30571の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000. Predicted molecular weight: 110-130 kDa.
Note: the molecular weight of the IFNNAR1 varies with cell line (different levels of glycosylation) in 293 and HeLa Cells; the mature form is ~110 - 130k. |
| 特記事項 |
|---|
|
WB
1/1000. Predicted molecular weight: 110-130 kDa. Note: the molecular weight of the IFNNAR1 varies with cell line (different levels of glycosylation) in 293 and HeLa Cells; the mature form is ~110 - 130k. |
ターゲット情報
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機能
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. -
組織特異性
IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266S. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. -
配列類似性
Belongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains. -
翻訳後修飾
Phosphorylated on tyrosine residues by TYK2 tyrosine kinase. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3454 Human
- Omim: 107450 Human
- SwissProt: P17181 Human
- Unigene: 529400 Human
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別名
- Alpha type antiviral protein antibody
- Antiviral protein, alpha-type antibody
- Antiviral protein, beta-type antibody
see all
画像
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Western blot - Anti-Interferon alpha/beta receptor 1 (phospho S535 + S539) antibody (ab30571)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab30571 は論文での使用が確認できていません。