Anti-Interferon alpha 2b 抗体 [9D3]
Anti-Interferon alpha 2b antibody [9D3]
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(11 Publications)
Mouse Monoclonal Interferon alpha 2 antibody. Suitable for sELISA, FuncS (Neut/Block) and reacts with Recombinant full length protein - Human, Human samples. Cited in 11 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IFNA2.
別名を表示する
IFNA2A, IFNA2B, IFNA2C, IFNA2, Interferon alpha-2, IFN-alpha-2, Interferon alpha-A, LeIF A
- sELISA
Unknown
Sandwich ELISA - Anti-Interferon alpha 2b antibody [9D3] (AB9386)
Standard curve for the determination of human interferon-alpha 2b by two-epitope ELISA : capture antibody 9D3 (ab9386), peroxidase-labeled antibody 4E10 (ab9388).
- FuncS (Neut/Block)
Unknown
Functional Studies (Neut/Block) - Anti-Interferon alpha 2b antibody [9D3] (AB9386)
Neutralizing activity of monoclonal antibody 9D3 in vitro. Interferon antiviral bioassay : L41 cells, mouse encephalomyacarditis virus (EMCV). Antibodies at 5 μg/ml. Control 1 - without EMCV (non-infected cells), control 2 - without interferon, control 3 - irrelevant antibody.
Reactivity data
製品の詳細
出荷温度及び保存条件
製品の状態
精製方法
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Interferon alpha 2b stimulates the immune system to attack pathogens by enhancing antigen presentation and activating natural killer cells and macrophages. It does not function as part of a complex and it acts independently to initiate an antiviral state in cells and increase the host's defense mechanisms. Its role in regulating cell growth and differentiation adds to its importance in maintaining immune homeostasis.
Pathways
Interferon alpha 2b is involved in the JAK-STAT signaling pathway which induces transcription of interferon-stimulated genes that orchestrate an immune response. Additionally it plays a role in the interferon signaling pathway which contributes to innate immunity. Proteins related to it through these pathways include STAT1 and STAT2 which collaborate with IFN alpha-b protein to transmit signals from extracellular stimuli to the nucleus resulting in gene activation.
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ターゲットの情報
文献 (11)
Recent publications for all applications. Explore the full list and refine your search
Applied microbiology and biotechnology 108:229 PubMed38393430
2024
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Journal of pharmaceutical analysis 12:308-316 PubMed35582401
2022
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World journal of stem cells 13:91-114 PubMed33584982
2021
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Microbial cell factories 15:104 PubMed27287473
2016
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Drug development and industrial pharmacy 42:890-6 PubMed26467418
2015
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PloS one 10:e0134723 PubMed26309247
2015
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Bioconjugate chemistry 26:452-9 PubMed25629733
2015
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Biotechnology letters 32:1271-7 PubMed20431909
2010
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WB
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Microbiological research 166:111-20 PubMed20227266
2010
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Blood 112:2657-66 PubMed18606876
2008
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