Anti-Integrin beta 5 抗体 (ab15459)
Key features and details
- Rabbit polyclonal to Integrin beta 5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Integrin beta 5 antibody
Integrin beta 5 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Integrin beta 5 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Hamster -
免疫原
Synthetic peptide within Human Integrin beta 5 aa 750 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P18084 -
特記事項
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab15459の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P | (1) |
1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. -
配列類似性
Belongs to the integrin beta chain family.
Contains 1 PSI domain.
Contains 1 VWFA domain. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3693 Human
- Entrez Gene: 16419 Mouse
- Entrez Gene: 257645 Rat
- Omim: 147561 Human
- SwissProt: P18084 Human
- SwissProt: O70309 Mouse
- Unigene: 536663 Human
- Unigene: 6424 Mouse
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別名
- FLJ26658 antibody
- Integrin beta-5 antibody
- Integrin subunit beta 5 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (29)
ab15459 は 29 報の論文で使用されています。
- Ma L et al. Integrin β5 is an independent prognostic marker for intrahepatic cholangiocarcinoma in a Chinese population. Exp Ther Med 26:532 (2023). PubMed: 37869645
- Bi J et al. Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin aVß5 receptor. J Cell Mol Med 24:996-1009 (2020). PubMed: 31701659
- Geng H et al. SHCBP1 Promotes Papillary Thyroid Carcinoma Carcinogenesis and Progression Through Promoting Formation of Integrin and Collagen and Maintaining Cell Stemness. Front Endocrinol (Lausanne) 11:613879 (2020). PubMed: 33716952
- Li Y et al. ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM. Front Cell Neurosci 12:489 (2018). PubMed: 30618636
- Lin Z et al. Integrin-ß5, a miR-185-targeted gene, promotes hepatocellular carcinoma tumorigenesis by regulating ß-catenin stability. J Exp Clin Cancer Res 37:17 (2018). PubMed: 29386044