Anti-Integrin alpha V 抗体 [RMV-7] (ab63490)
Key features and details
- Rat monoclonal [RMV-7] to Integrin alpha V
- Suitable for: IP, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG1
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Integrin alpha V antibody [RMV-7]
Integrin alpha V 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [RMV-7] to Integrin alpha V -
由来種
Rat -
アプリケーション
適用あり: IP, Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Integrin alpha V. Cultured LAK cells from Balb/c mice
Database link: P43406 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
RMV-7 -
ミエローマ
P3x63-Ag8.653 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63490の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
|
| Flow Cyt |
1/10 - 1/100.
ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10 µl of the suggested working dilution to label 106 cells in 100µl. |
| 特記事項 |
|---|
|
IP
Use at an assay dependent concentration. |
|
Flow Cyt
1/10 - 1/100. ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10 µl of the suggested working dilution to label 106 cells in 100µl. |
ターゲット情報
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機能
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 16410 Mouse
- SwissProt: P43406 Mouse
- Unigene: 227 Mouse
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別名
- antigen identified by monoclonal antibody L230 antibody
- CD 51 antibody
- CD51 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab63490 は 2 報の論文で使用されています。
- Khalifeh-Soltani A et al. Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids. Nat Med 20:175-83 (2014). PubMed: 24441829
- Gupton SL et al. Mena binds a5 integrin directly and modulates a5ß1 function. J Cell Biol 198:657-76 (2012). IF . PubMed: 22908313