Anti-Integrin alpha 9+beta 1 抗体 [Y9A2] (ab27947)
Key features and details
- Mouse monoclonal [Y9A2] to Integrin alpha 9+beta 1
- Suitable for: IP, ICC/IF, Flow Cyt
- Reacts with: Rat, Guinea pig, Human
- Isotype: IgG1
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Integrin alpha 9+beta 1 antibody [Y9A2] -
製品の詳細
Mouse monoclonal [Y9A2] to Integrin alpha 9+beta 1 -
由来種
Mouse -
特異性
Ab27947 recognises alpha9 integrin expressed as a heterodimer in association with the beta1 integrin. -
アプリケーション
適用あり: IP, ICC/IF, Flow Cytmore details
適用なし: IHC-FoFr,IHC-P or IHC-R -
種交差性
交差種: Rat, Guinea pig, Human -
免疫原
Tissue, cells or virus corresponding to Human Integrin alpha 9+beta 1. alpha9 integrin transfected lambda cells.
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特記事項
This clone (Y9A2) inhibits adhesion of alpha9 expressing cells to N terminal osteopontin.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Ab27947 was purified by affinity chromatography, from tissue culture supernatant. -
一次抗体 備考
This clone (Y9A2) inhibits adhesion of alpha9 expressing cells to N terminal osteopontin. -
ポリ/モノ
モノクローナル -
クローン名
Y9A2 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27947の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IP |
Use at an assay dependent concentration.
|
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| ICC/IF |
Use at an assay dependent concentration. PubMed: 20810886
|
|
| Flow Cyt |
Use at an assay dependent concentration.
(in 100ul). ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
IP
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. PubMed: 20810886 |
|
Flow Cyt
Use at an assay dependent concentration. (in 100ul). ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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関連性
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. Integrin alpha 9, when bound to the integrin beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of integrin alpha 9 has been found to be upregulated in small cell lung cancers. -
細胞内局在
Type I membrane protein. -
参照データベース
- Entrez Gene: 3680 Human
- Entrez Gene: 3688 Human
- Entrez Gene: 24511 Rat
- Entrez Gene: 685004 Rat
- Omim: 135630 Human
- Omim: 603963 Human
- SwissProt: P05556 Human
- SwissProt: Q13797 Human
see all -
別名
- CD29 antibody
- FNRB antibody
- GPIIA antibody
see all
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (14)
ab27947 は 14 報の論文で使用されています。
- Zhang X et al. Huogu injection protects against SONFH by promoting osteogenic differentiation of BMSCs and preventing osteoblast apoptosis. Cell Tissue Res 395:63-79 (2024). PubMed: 38040999
- Su X et al. FN-EDA mediates angiogenesis of hepatic fibrosis via integrin-VEGFR2 in a CD63 synergetic manner. Cell Death Discov 6:140 (2020). PubMed: 33293521
- Xu TJ et al. MiR-148a inhibits the proliferation and migration of glioblastoma by targeting ITGA9. Hum Cell 32:548-556 (2019). PubMed: 31489579
- Chen Y et al. Differentiation of human adipose derived stem cells into Leydig-like cells with molecular compounds. J Cell Mol Med 23:5956-5969 (2019). PubMed: 31293077
- Dereli Can G et al. A completely human-derived biomaterial mimicking limbal niche: Platelet-rich fibrin gel. Exp Eye Res 173:1-12 (2018). PubMed: 29678720
