Anti-Integrin alpha 2 抗体 [AK7] (ab30487)
![Flow Cytometry - Anti-Integrin alpha 2 antibody [AK7] (ab30487)](https://www.abcam.co.jp/ps/products/30/ab30487/Images/ab30487-40436-anti-integrin-alpha-2-antibody-ak7-flow-cytometry.jpg "Flow Cytometry - Anti-Integrin alpha 2 antibody [AK7] (ab30487)")
Key features and details
- Mouse monoclonal [AK7] to Integrin alpha 2
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-Integrin alpha 2 antibody [AK7]
Integrin alpha 2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [AK7] to Integrin alpha 2 -
由来種
Mouse -
アプリケーション
適用あり: Flow Cytmore details
適用なし: IHC-P -
種交差性
交差種: Human -
免疫原
The details of the immunogen for this antibody are not available.
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ポジティブ･コントロール
- Tonsil
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
AK7 -
ミエローマ
NS1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab30487の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
1/50 - 1/100.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
1/50 - 1/100. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3673 Human
- Omim: 192974 Human
- SwissProt: P17301 Human
- Unigene: 482077 Human
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別名
- BR antibody
- CD 49b antibody
- CD49 antigen like family member B antibody
see all
画像
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Flow Cytometry - Anti-Integrin alpha 2 antibody [AK7] (ab30487)Staining of human peripheral blood monocytes with MOUSE ANTI HUMAN CD49b (ab30487).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab30487 は 4 報の論文で使用されています。
- Ciarlet M et al. VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. J Virol 76:1109-23 (2002). PubMed: 11773387
- Yoshino N et al. Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies. Exp Anim 49:97-110 (2000). PubMed: 10889948
- Mazurov AV et al. A monoclonal antibody, VM64, reacts with a 130 kDa glycoprotein common to platelets and endothelial cells: heterogeneity in antibody binding to human aortic endothelial cells. Thromb Haemost 66:494-9 (1991). PubMed: 1796401
- Favaloro EJ et al. Co-expression of haemopoietic antigens on vascular endothelial cells: a detailed phenotypic analysis. Br J Haematol 74:385-94 (1990). PubMed: 2346720