Anti-Integrin alpha 1 抗体 [TS2/7] (ab34445)
![Flow Cytometry - Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)](https://www.abcam.co.jp/ps/products/34/ab34445/Images/ab34445-47790-anti-integrin-alpha-1-antibody-ts2-7-flow-cytometry.gif "Flow Cytometry - Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)")
Key features and details
- Mouse monoclonal [TS2/7] to Integrin alpha 1
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
Anti-Integrin alpha 1 antibody [TS2/7]
Integrin alpha 1 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [TS2/7] to Integrin alpha 1 -
由来種
Mouse -
特異性
ab34445 recognises alpha 1 integrin subunit. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Human Integrin alpha 1 subunit.
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ポジティブ･コントロール
- HeLa cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Purified from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
TS2/7 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab34445の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
1/25 - 1/50.
Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
| 特記事項 |
|---|
|
Flow Cyt
1/25 - 1/50. Use 10µl of the suggested working dilution to label 106 cells in 100µl.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
ターゲット情報
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機能
Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
ドメイン
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3672 Human
- Omim: 192968 Human
- SwissProt: P56199 Human
- Unigene: 644352 Human
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別名
- CD 49a antibody
- CD49 antigen-like family member A antibody
- CD49a antibody
see all
画像
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Flow Cytometry - Anti-Integrin alpha 1 antibody [TS2/7] (ab34445)Staining of HeLa cells with MOUSE ANTI HUMAN CD49a (ab34445).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab34445 は 3 報の論文で使用されています。
- Verma R et al. Integrin Ligation Results in Nephrin Tyrosine Phosphorylation In Vitro. PLoS One 11:e0148906 (2016). PubMed: 26848974
- Al Thawadi H et al. VE-cadherin cleavage by ovarian cancer microparticles induces ß-catenin phosphorylation in endothelial cells. Oncotarget 7:5289-305 (2016). WB . PubMed: 26700621
- Chen X et al. Integrin-mediated type II TGF-ß receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. J Clin Invest 124:3295-310 (2014). IHC-Fr, Flow Cyt ; Human . PubMed: 24983314