AB25034

Anti-IL-5 抗体 [QS-5]

Name: Anti-IL-5 抗体 [QS-5] (ab25034) | Abcam
Brand: Abcam Limited
SKU: AB25034
Price: 71000 JPY
Availability: InStock

Anti-IL-5 antibody [QS-5]

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(4 Publications)

Mouse Monoclonal IL-5 antibody. Suitable for ELISA, WB, FuncS (Neut/Block), ELISPOT, IHC-Fr and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL5.

別名を表示する

Interleukin-5, IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF, IL5

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

QS-5

アイソタイプ

IgG1

キャリアフリー

交差種

Human

アプリケーション

FuncS (Neut/Block), WB, IHC-Fr, ELISA, ELISPOT

applications

免疫原

Recombinant Full Length Protein corresponding to Human IL5.

P05113

特異性

Binds with high efficiency to natural and recombinant human IL5.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"}, "ELISPOT" : {"fullname" : "ELISPOT", "shortname":"ELISPOT"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "", "ELISPOT-species-checked": "guaranteed", "ELISPOT-species-dilution-info": "", "ELISPOT-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Ion exchange chromatography

バッファー組成

Constituents: PBS, 4.275% Trehalose

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed : 2653458, PubMed : 9010276). Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB (PubMed : 1495999, PubMed : 22528658). Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (PubMed : 7613138).

See full target information IL5

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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Experimental dermatology 27:1328-1335 PubMed30230040

2018

Down-regulated SHARPIN may accelerate the development of atopic dermatitis through activating interleukin-33/ST2 signalling.

Applications

Unspecified application

Species

Unspecified reactive species

Lingjie Tang,Jiaman Wang,Jingna Zhu,Yanhua Liang

The Journal of allergy and clinical immunology 142:1489-1499.e23 PubMed30102935

2018

IgD-activated mast cells induce IgE synthesis in B cells in nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Guan-Ting Zhai,Hai Wang,Jing-Xian Li,Ping-Ping Cao,Wen-Xiu Jiang,Jia Song,Yin Yao,Zhi-Chao Wang,Zhe-Zheng Wang,Meng-Chen Wang,Bo Liao,Qi-Miao Feng,Xiang Lu,Heng Wang,Peisong Gao,Zheng Liu

International forum of allergy & rhinology 4:453-62 PubMed24504744

2014

Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Daishi Chen,Mingfeng Mao,Luisa M Bellussi,Desiderio Passali,Lei Chen

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 32:386-92 PubMed23349558

2013

The role of High Mobility Group Box 1 chromosomal protein in the pathogenesis of chronic sinusitis and nasal polyposis.

Applications

IHC

Species

Unspecified reactive species

L M Bellussi,L Chen,D Chen,F M Passali,D Passali

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-5 抗体 [QS-5]

Anti-IL-5 antibody [QS-5]

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

交差種

アプリケーション

免疫原

特異性

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (4)

代替製品

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組合せ製品

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise