Anti-IL-4 抗体 [MP4-25D2] (ab34277)
![Western blot - Anti-IL-4 antibody [MP4-25D2] (ab34277)](https://www.abcam.co.jp/ps/products/34/ab34277/Images/ab34277-47631-anti-il-4-antibody-mp4-25d2-western-blot.jpg "Western blot - Anti-IL-4 antibody [MP4-25D2] (ab34277)")
Key features and details
- Rat monoclonal [MP4-25D2] to IL-4
- Suitable for: WB
- Reacts with: Human, Rhesus monkey
- Isotype: IgG1
製品の概要
-
製品名
Anti-IL-4 antibody [MP4-25D2]
IL-4 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [MP4-25D2] to IL-4 -
由来種
Rat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human, Rhesus monkey -
免疫原
Recombinant full length protein corresponding to Human IL-4.
-
特記事項
This clone is reported to neutralise IL4 activity.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
This antibody was purified tissue culture supernatant. -
一次抗体 備考
This clone is reported to neutralise IL4 activity. -
ポリ/モノ
モノクローナル -
クローン名
MP4-25D2 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab34277の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 17 kDa.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 17 kDa. |
ターゲット情報
-
機能
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. -
関連疾患
Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. -
配列類似性
Belongs to the IL-4/IL-13 family. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 3565 Human
- Entrez Gene: 574281 Rhesus monkey
- Omim: 147780 Human
- SwissProt: P05112 Human
- SwissProt: P51492 Rhesus monkey
- Unigene: 73917 Human
-
別名
- B cell growth factor 1 antibody
- B cell IgG differentiation factor antibody
- B Cell Stimulatory Factor 1 antibody
see all
画像
-
Western blot - Anti-IL-4 antibody [MP4-25D2] (ab34277)Anti-IL-4 antibody [MP4-25D2] (ab34277) at 1/500 dilution + human recombinant IL4 protein.
Secondary
Rabbit anti Rat IgG HRP
Predicted band size: 17 kDa
Observed band size: 17 kDa
Additional bands at: 30 kDa. We are unsure as to the identity of these extra bands.
The arrow next to the image points to human IL4.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab34277 は論文での使用が確認できていません。