Anti-IL-2 抗体 [JES6-1A12] (ab11510)
Key features and details
- Rat monoclonal [JES6-1A12] to IL-2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2a
製品の概要
-
製品名
Anti-IL-2 antibody [JES6-1A12]
IL-2 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [JES6-1A12] to IL-2 -
由来種
Rat -
特異性
ab11510 recognises natural and recombinant mouse IL2. We have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse IL-2.
-
特記事項
Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
-
精製度
Protein G purified -
特記事項(精製)
Purified IgG prepared by affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
JES6-1A12 -
アイソタイプ
IgG2a -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab11510の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 20.28 kDa.
|
特記事項 |
---|
WB
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 20.28 kDa. |
ターゲット情報
-
機能
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. -
関連疾患
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. -
配列類似性
Belongs to the IL-2 family. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 16183 Mouse
- SwissProt: P04351 Mouse
- Unigene: 14190 Mouse
-
別名
- Aldesleukin antibody
- IL 2 antibody
- IL-2 antibody
see all
画像
データシートおよび資料
-
Datasheet download
参考文献 (2)
ab11510 は 2 報の論文で使用されています。
- Li X et al. Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice. Front Immunol 14:1185921 (2023). PubMed: 37228612
- Huang Y et al. The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice. Reprod Biol Endocrinol 19:14 (2021). PubMed: 33494759