Anti-IL-1F10 抗体 - C-terminal (ab180898)
Key features and details
- Rabbit polyclonal to IL-1F10 - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-1F10 antibody - C-terminal -
製品の詳細
Rabbit polyclonal to IL-1F10 - C-terminal -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide corresponding to Human IL-1F10 (C terminal). Peptide corresponds to 17 amino acids. NP_775184
Database link: Q8WWZ1 -
ポジティブ･コントロール
- Human liver tissue lysate and Human spleen tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab180898の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 5 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 17 kDa).
|
| 特記事項 |
|---|
|
IHC-P
Use a concentration of 5 µg/ml. |
|
WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 17 kDa). |
ターゲット情報
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機能
Binds soluble IL-1 receptor type 1. -
組織特異性
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. -
配列類似性
Belongs to the IL-1 family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 84639 Human
- Entrez Gene: 215274 Mouse
- Entrez Gene: 362077 Rat
- Omim: 615296 Human
- SwissProt: Q8WWZ1 Human
- SwissProt: Q8R459 Mouse
- Unigene: 306974 Human
- Unigene: 218750 Mouse
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別名
- family of interleukin 1-theta antibody
- FIL1 theta antibody
- FIL1T antibody
see all
画像
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Western blot - Anti-IL-1F10 antibody - C-terminal (ab180898)All lanes : Anti-IL-1F10 antibody - C-terminal (ab180898) at 1 µg
Lane 1 : Human liver tissue lysate with Absent
Lane 2 : Human liver tissue lysate with Present
Lysates/proteins at 15 µg per lane.
Predicted band size: 17 kDa
Observed band size: 20 kDa why is the actual band size different from the predicted? -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-1F10 antibody - C-terminal (ab180898)Immunohistochemical analysis of paraffin-embedded Human spleen tissue, labeling IL1F10 using ab180898 at 5 μg/mL.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab180898 は 3 報の論文で使用されています。
- Zhou H et al. Interleukin-38 promotes skin tumorigenesis in an IL-1Rrp2-dependent manner. EMBO Rep 23:e53791 (2022). PubMed: 35578812
- Wei Y et al. Interleukin-38 alleviates cardiac remodelling after myocardial infarction. J Cell Mol Med 24:371-384 (2020). PubMed: 31746138
- Chen F et al. Interleukin-38 in colorectal cancer: a potential role in precision medicine. Cancer Immunol Immunother 69:69-79 (2020). PubMed: 31786620
