Anti-IL-19 抗体 [EPNCIR168] (ab154187)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPNCIR168] to IL-19
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
Related conjugates and formulations
製品の概要
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製品名
Anti-IL-19 antibody [EPNCIR168]
IL-19 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPNCIR168] to IL-19 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details
適用なし: IHC-P or IP -
種交差性
交差種: Mouse, Human -
免疫原
Full length protein corresponding to Mouse IL-19.
Database link: Q8CJ70 -
ポジティブ・コントロール
- Mouse IL19 recombinant protein; U937 cells
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特記事項
This antibody was developed as part of a collaboration between the National Cancer Institute's Center for Cancer Research and the lab of Juergen Mueller. View antibodies from NCI Center for Cancer Research Collaboration.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20ºC. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPNCIR168 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154187の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 20 kDa.
|
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ICC/IF |
1/50 - 1/100.
|
特記事項 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 20 kDa. |
ICC/IF
1/50 - 1/100. |
ターゲット情報
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機能
May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. -
配列類似性
Belongs to the IL-10 family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 29949 Human
- Entrez Gene: 329244 Mouse
- Omim: 605687 Human
- SwissProt: Q9UHD0 Human
- SwissProt: Q8CJ70 Mouse
- Unigene: 661017 Human
- Unigene: 131480 Mouse
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別名
- IL 10C antibody
- IL 19 antibody
- IL-19 antibody
see all
画像
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Anti-IL-19 antibody [EPNCIR168] (ab154187) at 1/1000 dilution + Mouse IL19 recombinant protein at 0.01 µg
Predicted band size: 20 kDa -
Immunofluorescent analysis of U937 cells labeling IL19 with ab154187 at 1/50 dilution
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab154187 は 5 報の論文で使用されています。
- Barada O et al. IL-20 Cytokines Are Involved in the Repair of Airway Epithelial Barrier: Implication in Exposure to Cigarette Smoke and in COPD Pathology. Cells 12:N/A (2023). PubMed: 37887308
- Wang Y et al. Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway. Mediators Inflamm 2022:6755407 (2022). PubMed: 35281428
- Le Roux M et al. IL-20 Cytokines Are Involved in Epithelial Lesions Associated with Virus-Induced COPD Exacerbation in Mice. Biomedicines 9:N/A (2021). PubMed: 34944654
- Tao K et al. LncRNA CASC11 improves atherosclerosis by downregulating IL-9 and regulating vascular smooth muscle cell apoptosis and proliferation. Biosci Biotechnol Biochem N/A:1-5 (2019). PubMed: 30915898
- Madouri F et al. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae. EBioMedicine 37:417-427 (2018). PubMed: 30361066