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AB39418

Anti-IL-13 receptor alpha 1 抗体 [GM1E7]

Anti-IL-13 receptor alpha 1 antibody [GM1E7]

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(1 Publication)

Mouse Monoclonal IL-13 receptor alpha 1 antibody. Carrier free. Suitable for Flow Cyt, ICC/IF and reacts with Transfected cell line samples. Cited in 1 publication.

別名を表示する

CD213a1, IL13R, IL13RA, IL13RA1, Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Immunofluorescence staining of CHO cells using ab39418 at 1 μg/106 cells. CHO cells were transiently transfected with an expression vector encoding IL13-R. Binding of ab39418 was visualized with a FITC-conjugated secondary antibody (green). Actin filaments are labeled with Alexa Fluor-555 Phalloidin (red). Cell nuclei are stained with DAPI (blue).

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Flow cytometric analysis of BOSC23 cells using ab39418. BOSC23 cells were transiently transfected with an expression vector encoding either IL13-R (red curve) or an irrelevant protein (control transfectant : black curve). Binding of ab39418 was detected with a PE-conjugated secondary antibody. A positive signal was obtained only with IL13-R transfected cells.

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)
  • Flow Cyt

Unknown

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Specificity testing of ab39418. BOSC cells were transiently transfected with an expression vector encoding either the extracellular domain of IL-13Rα1 or an irrelevant protein. Expression of the constructs was tested with an anti-tag monoclonal antibody (B, green curves), an irrelevant monoclonal antibody served as negative control (bluecurves). For specificity testing (A), purified ab39418 was tested on both the IL-13Rα1 (red curve) and the irrelevant protein trans-fectants (green curve). A posi-tive signal was obtained only with IL-13Rα1 transfected cells.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

GM1E7

アイソタイプ

IgG1

キャリアフリー

Yes

アプリケーション

Flow Cyt, ICC/IF

applications

特異性

The antibody recognises IL-13 Receptor 1 alpha transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Transfected cell line": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": " for 10^6 Cells", "ICCIF-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
See full target information IL13RA1

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal for immunotherapy of cancer 8: PubMed32616554

2020

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Marta Trüb,Franziska Uhlenbrock,Christina Claus,Petra Herzig,Martin Thelen,Vaios Karanikas,Marina Bacac,Maria Amann,Rosemarie Albrecht,Claudia Ferrara-Koller,Daniela Thommen,Sacha Rothschield,Spasenija Savic Prince,Kirsten D Mertz,Gieri Cathomas,Robert Rosenberg,Viola Heinzelmann-Schwarz,Mark Wiese,Didier Lardinois,Pablo Umana,Christian Klein,Heinz Laubli,Abhishek S Kashyap,Alfred Zippelius
View all publications

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