Anti-IL-13 receptor alpha 1 抗体 (ab108499)
Key features and details
- Rabbit polyclonal to IL-13 receptor alpha 1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-13 receptor alpha 1 antibody
IL-13 receptor alpha 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IL-13 receptor alpha 1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant fragment corresponding to Human IL-13 receptor alpha 1 aa 70-304.
Database link: BC015768 -
ポジティブ･コントロール
- A549 cell lysate. Human fetal heart tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute in 200ul sterile H2O. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituent: 1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab108499の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
1/500 - 1/1000. Predicted molecular weight: 49 kDa.
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| IHC-P |
1/100 - 1/500.
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| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 49 kDa. |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. -
組織特異性
Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells. -
配列類似性
Belongs to the type I cytokine receptor family. Type 5 subfamily. -
ドメイン
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3597 Human
- Entrez Gene: 16164 Mouse
- Entrez Gene: 252963 Rat
- Omim: 300119 Human
- SwissProt: P78552 Human
- SwissProt: O09030 Mouse
- Unigene: 496646 Human
- Unigene: 24208 Mouse
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別名
- bB128O4.2.1 (interleukin 13 receptor, alpha 1) antibody
- Cancer/testis antigen 19 antibody
- CD213a1 antibody
see all
画像
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Western blot - Anti-IL-13 receptor alpha 1 antibody (ab108499)Anti-IL-13 receptor alpha 1 antibody (ab108499) at 1/500 dilution + A549 cell lysate
Predicted band size: 49 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-13 receptor alpha 1 antibody (ab108499)1/100 ab108499 staining IL13 receptor alpha 1 in formalin-fixed, paraffin-embedded Human fetal heart tissue.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab108499 は 2 報の論文で使用されています。
- Dutta AK et al. Signaling through the interleukin-4 and interleukin-13 receptor complexes regulates cholangiocyte TMEM16A expression and biliary secretion. Am J Physiol Gastrointest Liver Physiol 318:G763-G771 (2020). PubMed: 32090602
- Wang X et al. Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing. Front Bioeng Biotechnol 7:360 (2019). PubMed: 31921796