Anti-IL-12 p70 抗体 [QS-12p70] (ab25036)
Key features and details
- Mouse monoclonal [QS-12p70] to IL-12 p70
- Suitable for: ELISA, ELISpot, Neutralising
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-IL-12 p70 antibody [QS-12p70] -
製品の詳細
Mouse monoclonal [QS-12p70] to IL-12 p70 -
由来種
Mouse -
特異性
ab25036 recognises IL-12p70 heterodimer, but shows no reactivity with the p35 or p40 monomer. -
アプリケーション
適用あり: ELISA, ELISpot, Neutralisingmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein corresponding to Human IL-12 p70.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Constituents: PBS, 4.275% Trehalose -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
QS-12p70 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab25036の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA | ||
ELISpot | ||
Neutralising |
特記事項 |
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ELISPOT: Use at an assay dependent dilution.
In vitro Neut: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
IL-12 p70 is a disulfide bonded heterodimer of the IL-12 40 kDa and 35 kDa subunits. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 3592 Human
- Entrez Gene: 3593 Human
- Omim: 161560 Human
- Omim: 161561 Human
- SwissProt: P29459 Human
- SwissProt: P29460 Human
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別名
- IL12A antibody
- IL12B antibody
- CLMF p35 antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (3)
ab25036 は 3 報の論文で使用されています。
- Zheng G et al. Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab. Signal Transduct Target Ther 6:236 (2021). PubMed: 34158475
- Sierra JM et al. Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation. Front Immunol 12:745939 (2021). PubMed: 34616407
- Le Page ME et al. Killer Ig-like receptor 2DL4 does not mediate NK cell IFN-? responses to soluble HLA-G preparations. J Immunol 192:732-40 (2014). PubMed: 24337374