AB50

Anti-IL-12 p40 抗体 [1-1A4]

Name: Anti-IL-12 p40 抗体 [1-1A4] (ab50) | Abcam
Brand: Abcam Limited
SKU: AB50
Price: 75000 JPY
Availability: InStock

Anti-IL-12 p40 antibody [1-1A4]

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(7 Publications)

Mouse Monoclonal IL-12B antibody. Suitable for ELISA, RIA and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Fragment Protein within Human IL12B.

別名を表示する

NKSF2, IL12B, Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2, CLMF p40

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

1-1A4

アイソタイプ

IgG1

軽鎖のタイプ

unknown

キャリアフリー

交差種

Human

アプリケーション

RIA, ELISA

applications

免疫原

Recombinant Fragment Protein within Human IL12B. The exact immunogen used to generate this antibody is proprietary information.

P29460

特異性

Recognises p35/40 heterodimer and p40. Used against CCHO and Baculovirus derived recombinant IL-12. Reacts with stimulated and unstimulated monocytes.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "RIA" : {"fullname" : "Radioimmunoassay", "shortname":"RIA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "RIA-species-checked": "guaranteed", "RIA-species-dilution-info": "", "RIA-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

Preservative: 0.02% Sodium azide Constituents: PBS

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

See full target information IL12B

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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

Proceedings of the National Academy of Sciences of 117:26460-26469 PubMed33020308

2020

Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence.

Applications

Unspecified application

Species

Unspecified reactive species

Craig T Werner,Swarup Mitra,Benjamin D Auerbach,Zi-Jun Wang,Jennifer A Martin,Andrew F Stewart,Pedro H Gobira,Madoka Iida,Chunna An,Moriah M Cobb,Aaron Caccamise,Richard J Salvi,Rachael L Neve,Amy M Gancarz,David M Dietz

Cancer management and research 11:10011-10028 PubMed31819634

2019

Simvastatin Evokes An Unpredicted Antagonism For Tamoxifen In MCF-7 Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Amel B Ibrahim,Hala F Zaki,Walaa Wadie,Mervat M Omran,Samia A Shouman

Oxidative medicine and cellular longevity 2019:5820839 PubMed31871552

2019

Internalization and Transportation of Endothelial Cell Surface K2.3 and K3.1 in Normal Pregnancy and Preeclampsia.

Applications

Unspecified application

Species

Unspecified reactive species

Shinkyu Choi,Ji Aee Kim,Seikwan Oh,Mi Hye Park,Geum Joon Cho,Suk Hyo Suh

Antioxidants (Basel, Switzerland) 8: PubMed31690052

2019

Dietary EPA Increases Rat Mortality in Diabetes Mellitus, A Phenomenon Which Is Compensated by Green Tea Extract.

Applications

Unspecified application

Species

Unspecified reactive species

Thibault Leger,Beibei He,Kasra Azarnoush,Chrystèle Jouve,Jean-Paul Rigaudiere,Florent Joffre,Damien Bouvier,Vincent Sapin,Bruno Pereira,Luc Demaison

Oxidative medicine and cellular longevity 2019:7536803 PubMed31781348

2019

The 5-Lipoxygenase Inhibitor Zileuton Protects Pressure Overload-Induced Cardiac Remodeling via Activating PPAR.

Applications

Unspecified application

Species

Unspecified reactive species

Qing-Qing Wu,Wei Deng,Yang Xiao,Jiao-Jiao Chen,Chen Liu,Juan Wang,Yankai Guo,Mingxia Duan,Zhulan Cai,Saiyang Xie,Yuan Yuan,Qizhu Tang

The EMBO journal 38:e100312 PubMed31368593

2019

Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion.

Applications

Unspecified application

Species

Unspecified reactive species

Takashi Baba,Daniel J Toth,Nivedita Sengupta,Yeun Ju Kim,Tamas Balla

Hybridoma 16:363-9 PubMed9309427

1997

Production and characterization of monoclonal antibodies to human interleukin-12.

Applications

Unspecified application

Species

Unspecified reactive species

R W Carter,P M Patel,A J Stanley,E Ingham,M Wadhwa,C Bird,R Thorpe,P J Selby,R E Banks

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-12 p40 抗体 [1-1A4]

Anti-IL-12 p40 antibody [1-1A4]

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

キャリアフリー

交差種

アプリケーション

免疫原

特異性

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (7)

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Abcam product promise