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AB9574

Anti-IGF2 抗体

Anti-IGF2 antibody

4

(20 Reviews)

|

(108 Publications)

Anti-IGF2 antibody (ab9574) is a rabbit polyclonal antibody detecting IGF2 in Western Blot, ELISA.

- Over 100 publications
- Trusted since 2002

別名を表示する

IGF-2, PP1446, IGF2, Insulin-like growth factor 2, Insulin-like growth factor II, Somatomedin-A, T3M-11-derived growth factor, IGF-II

2 Images
Western blot - Anti-IGF2 antibody (AB9574)
  • WB

Unknown

Western blot - Anti-IGF2 antibody (AB9574)

Rabbit Anti-Human IGF-II against Human IGF-II. Antibody concentration : 0.10 ug/ml Lower limit of detection : 3.91 ng/lane Molecular Weight : 7.5 kDa
Lane 1 : Marker
Lane 2 : 250 ng
Lane 3 : 125 ng
Lane 4 : 62.5 ng
Lane 5 : 31.25 ng
Lane 6 : 15.625 ng
Lane 7 : 7.8 ng
Lane 8 : 3.9 ng

All lanes:

Western blot - Anti-IGF2 antibody (ab9574)

Predicted band size: 20 kDa

false

Sandwich ELISA - Anti-IGF2 antibody (AB9574)
  • sELISA

Unknown

Sandwich ELISA - Anti-IGF2 antibody (AB9574)

ab9574 detecting IGF2 using sandwich ELISA

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

軽鎖のタイプ

unknown

キャリアフリー

No

アプリケーション

sELISA, WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human IGF2.

P01344

Reactivity data

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製品の詳細

What is this antibody validated in?
Anti-IGF2 antibody (ab9574) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), ELISA. Trusted by the scientific community
Anti-IGF2 (ab9574) was first used in a scientific publication in 2002 and has been cited over 100 times in peer-reviewed journals.

Reviewed by scientists
Anti-IGF2 (ab9574) has over 20 independent reviews from customers.

出荷温度及び保存条件

製品の状態
Lyophilized
再構成
reconstitute with water at 200µL
精製方法
Affinity purification Immunogen
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed : 28873464). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate (By similarity).. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as a physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
See full target information IGF2

文献 (108)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine (Cambridge, Mass.) 29:161 PubMed38017373

2023

IGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in D-galactose-induced aging mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohai Zhou,Bowen Tan,Weiwei Gui,Caiping Zhou,Hanxin Zhao,Xihua Lin,Hong Li

International journal of biological sciences 19:2409-2427 PubMed37215980

2023

Brain-derived extracellular vesicles promote bone-fat imbalance in Alzheimer's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Xixi Liu,Chunyuan Chen,Yaling Jiang,Meidan Wan,Bin Jiao,Xinxin Liao,Shanshan Rao,Chungu Hong,Qijie Yang,Yuan Zhu,Qianqian Liu,Zhongwei Luo,Ran Duan,Yiyi Wang,Yijuan Tan,Jia Cao,Zhengzhao Liu,Zhenxing Wang,Hui Xie,Lu Shen

Cell 185:2213-2233.e25 PubMed35750033

2022

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.

Applications

Unspecified application

Species

Unspecified reactive species

Julia Tcw,Lu Qian,Nina H Pipalia,Michael J Chao,Shuang A Liang,Yang Shi,Bharat R Jain,Sarah E Bertelsen,Manav Kapoor,Edoardo Marcora,Elizabeth Sikora,Elizabeth J Andrews,Alessandra C Martini,Celeste M Karch,Elizabeth Head,David M Holtzman,Bin Zhang,Minghui Wang,Frederick R Maxfield,Wayne W Poon,Alison M Goate

Nature communications 13:2083 PubMed35440587

2022

Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.

Applications

Unspecified application

Species

Unspecified reactive species

Norman L Lehman,Nathalie Spassky,Müge Sak,Amy Webb,Cory T Zumbar,Aisulu Usubalieva,Khaled J Alkhateeb,Joseph P McElroy,Kirsteen H Maclean,Paolo Fadda,Tom Liu,Vineela Gangalapudi,Jamie Carver,Zied Abdullaev,Cynthia Timmers,John R Parker,Christopher R Pierson,Bret C Mobley,Murat Gokden,Eyas M Hattab,Timothy Parrett,Ralph X Cooke,Trang D Lehman,Stefan Costinean,Anil Parwani,Brian J Williams,Randy L Jensen,Kenneth Aldape,Akshitkumar M Mistry

Bioengineered 13:7986-7999 PubMed35293283

2022

Magnesium isoglycyrrhizinate suppresses bladder cancer progression by modulating the miR-26b/Nox4 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhihao Yuan,Guancheng Guo,Guifang Sun,Qi Li,Lihui Wang,Baoping Qiao

Innate immunity 28:37-48 PubMed35142578

2022

Circ_0026579 alleviates LPS-induced WI-38 cells inflammation injury in infantile pneumonia.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Yu,Tingting Yang,Zhaozheng Ding,Yuan Cao

Scientific reports 12:2038 PubMed35132125

2022

Insulin-like growth factor 2 and autophagy gene expression alteration arise as potential biomarkers in Parkinson's disease.

Applications

Unspecified application

Species

Unspecified reactive species

Denisse Sepúlveda,Felipe Grunenwald,Alvaro Vidal,Paulina Troncoso-Escudero,Marisol Cisternas-Olmedo,Roque Villagra,Pedro Vergara,Carlos Aguilera,Melissa Nassif,Rene L Vidal

PloS one 16:e0260887 PubMed34855889

2021

Intrathecal IGF2 siRNA injection provides long-lasting anti-allodynic effect in a spared nerve injury rat model of neuropathic pain.

Applications

Unspecified application

Species

Unspecified reactive species

Wei-Hung Chan,Nian-Cih Huang,Yi-Wen Lin,Feng-Yen Lin,Chien-Sung Tsai,Chun-Chang Yeh

Cancers 13: PubMed34062786

2021

Phosphodiesterase 4D Depletion/Inhibition Exerts Anti-Oncogenic Properties in Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Federica Ragusa,Nadia Panera,Silvia Cardarelli,Marco Scarsella,Marzia Bianchi,Stefano Biagioni,Mauro Giorgi,Anna Alisi,Mara Massimi

Theranostics 11:5585-5604 PubMed33859765

2021

Targeting long noncoding RNA PMIF facilitates osteoprogenitor cells migrating to bone formation surface to promote bone formation during aging.

Applications

Unspecified application

Species

Unspecified reactive species

Dijie Li,Jin Liu,Chaofei Yang,Ye Tian,Chong Yin,Lifang Hu,Zhihao Chen,Fan Zhao,Ru Zhang,Aiping Lu,Ge Zhang,Airong Qian
View all publications

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