AB18954

Anti-IGF2 抗体

Anti-IGF2 antibody

JP Deleterious:医薬用外劇物

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(2 Publications)

Rabbit Polyclonal IGF2 antibody. Suitable for WB, sELISA and reacts with Recombinant full length protein - Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IGF2.

別名を表示する

IGF-2, PP1446, IGF2, Insulin-like growth factor 2, Insulin-like growth factor II, Somatomedin-A, T3M-11-derived growth factor, IGF-II

2 Images

Supplier Data

Western blot - Anti-IGF2 antibody (AB18954)

Western blot analysis of IGF-II using recombinant human IGF-II.

Lane 1;50ng

Lane 2;250 ng

Lane 3;500 ng

All lanes:

Western blot - Anti-IGF2 antibody (ab18954)

Predicted band size: 20 kDa

false

Sandwich ELISA - Anti-IGF2 antibody (AB18954)

sELISA

Unknown

Sandwich ELISA - Anti-IGF2 antibody (AB18954)

Standard Curve for IGF2 (Analyte : ab9575) dilution range 1pg/ml to 1ug/ml using Capture Antibody Rat monoclonal [RM0100-3J42] to IGF2 (ab86485) at 1ug/ml and Detector Antibody Rabbit polyclonal to IGF2 (ab18954) at 0.5ug/ml.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

アプリケーション

sELISA, WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human IGF2.

P01344

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-4 µg/mL", "WB-species-notes": "<p></p>", "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "0.5 µg/mL", "sELISA-species-notes": "<p>For sandwich ELISA, use this antibody as Detection at 0.5μg/ml with <a href='/products/primary-antibodies/igf2-antibody-rm0100-3j42-ab86485'>ab86485</a> as Capture.</p>" } } }

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製品の詳細

This product is manufactured by BioVision, an Abcam company and was previously called 5122 IGF-II Antibody. 5122-100 is the same size as the 100 µg size of ab18954.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Immunogen

バッファー組成

pH: 7.2 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA

出荷温度

Blue Ice

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed : 28873464). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate (By similarity).. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as a physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.

See full target information IGF2

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Inflammopharmacology 33:3479-3498 PubMed40325262

2025

Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer's disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress.

Applications

Unspecified application

Species

Unspecified reactive species

Ebtsam S Abdel-Lah,Hoda S Sherkawy,Wafaa H Mohamed,Mariam A Fawy,Asmaa A Hasan,Asmaa A Muhammed,Amira F Taha,Abeer A Tony,Nashwa Hamad,Marwa G Gamea

International journal of biological sciences 16:2938-2950 PubMed33061807

2020

Lnc-MCEI mediated the chemosensitivity of esophageal squamous cell carcinoma via miR-6759-5p to competitively regulate IGF2.

Applications

Unspecified application

Species

Unspecified reactive species

Guangming Liu,Wei Guo,Guang Chen,Wencan Li,Youbin Cui,Junjie Qin,Jing Peng

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IGF2 抗体

Anti-IGF2 antibody

Western blot - Anti-IGF2 antibody (AB18954)

Sandwich ELISA - Anti-IGF2 antibody (AB18954)

Key facts

宿主種

クローン性

アイソタイプ

キャリアフリー

アプリケーション

免疫原

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

長期保存温度

分注に関する情報

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (2)

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Abcam product promise