Anti-IgE 抗体 [4C3] (ab106494)
![Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)](https://www.abcam.co.jp/ps/products/106/ab106494/Images/ab106494-118874-anti-ige-antibody-4c3-sandwich-elisa.jpg "Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)")
Key features and details
- Mouse monoclonal [4C3] to IgE
- Suitable for: Sandwich ELISA
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-IgE antibody [4C3]
IgE 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [4C3] to IgE -
由来種
Mouse -
特異性
ab106494 is specific for Human IgE. It reacts with IgE purified from blood but does not cross-react with Human anti-IgG1, IgG2, IgG3, IgG4, IgA and IgM
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アプリケーション
適用あり: Sandwich ELISAmore details -
種交差性
交差種: Human
非交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Human IgE aa 1-550.
Database link: P01854 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
4C3 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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ELISA pair antibody
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106494の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Sandwich ELISA |
Use a concentration of 5 µg/ml.
for coating plates. Use ab106493 for detection. |
| 特記事項 |
|---|
|
Sandwich ELISA
Use a concentration of 5 µg/ml. for coating plates. Use ab106493 for detection. |
ターゲット情報
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関連性
IgE is the class of antibodies produced in the lungs, skin, and mucous membranes. It may protect against parasite invasion, but it is a major factor in allergic reactions. The antigen-specific IgE interacts with mast cells and eosinophils, triggers the release of histamine, leukotrienes and other substances that lead to the itching, sneezing and congestion of allergies - and the life threatening respiratory distress of asthma and anaphylactic shock. -
細胞内局在
Cell Membrane -
参照データベース
- Entrez Gene: 3497 Human
- Omim: 147180 Human
- SwissProt: P01854 Human
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別名
- Igh2 antibody
- IGHE antibody
- IGHEP1 antibody
- Immunoglobulin heavy constant epsilon antibody
画像
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Sandwich ELISA - Anti-IgE antibody [4C3] (ab106494)ab106494 used at 5 µg/ml for coating ELISA plates to capture Human IgE. Detection utilised ab106493 at 1/1000 dilution.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab106494 は 2 報の論文で使用されています。
- Zhang Y et al. An allergenic plant calmodulin from Artemisia pollen primes human DCs leads to Th2 polarization. Front Immunol 13:996427 (2022). PubMed: 36248805
- Leung S et al. Multiplexed immunoassay approach to characterize antidrug antibody like specific reactivity. Bioanalysis 11:703-712 (2019). PubMed: 30994012