Anti-IB-2 抗体 (ab65211)
Key features and details
- Rabbit polyclonal to IB-2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-IB-2 antibody
IB-2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IB-2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide corresponding to Human IB-2.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65211の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 88 kDa (predicted molecular weight: 88 kDa).
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 88 kDa (predicted molecular weight: 88 kDa). |
ターゲット情報
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機能
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. -
組織特異性
Expressed mainly in the brain and pancreas, including insulin-secreting cells. In the nervous system, more abundantly expressed in the cerebellum, pituitary gland, occipital lobe and the amygdala. Also expressed in fetal brain. Very low levels found in uterus, ovary, prostate, colon, testis, adrenal gland, thyroid gland and salivary gland. -
配列類似性
Belongs to the JIP scaffold family.
Contains 1 PID domain.
Contains 1 SH3 domain. -
細胞内局在
Cytoplasm. Accumulates in cell surface projections. - Information by UniProt
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参照データベース
- Entrez Gene: 60597 Mouse
- SwissProt: Q9ERE9 Mouse
- Unigene: 173337 Mouse
- Unigene: 482169 Mouse
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別名
- C jun amino terminal kinase interacting protein 2 antibody
- C-jun-amino-terminal kinase-interacting protein 2 antibody
- Homologous to mouse JIP 1 antibody
see all
画像
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Western blot - Anti-IB-2 antibody (ab65211)All lanes : Anti-IB-2 antibody (ab65211) at 1/500 dilution
Lane 1 : Extracts from mouse brain cells
Lane 2 : Extracts from mouse brain cells, plus immunising peptide
Predicted band size: 88 kDa
Observed band size: 88 kDa
Additional bands at: 30 kDa. We are unsure as to the identity of these extra bands.
The amount of positive control loading for the WB is 5-30 ug of total protein.The amount of the peptide for the WB is 5-10 ug.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab65211 は論文での使用が確認できていません。