Anti-Human Serum Albumin 抗体 (ab19180)
Key features and details
- Goat polyclonal to Human Serum Albumin
- Suitable for: ICC, ELISA, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Human Serum Albumin antibody
Human Serum Albumin 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Human Serum Albumin -
由来種
Goat -
アプリケーション
適用あり: ICC, ELISA, WBmore details -
種交差性
交差種: Human -
免疫原
Full length protein corresponding to Human Human Serum Albumin. Serum albumin
Database link: P02768 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 6.8
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab19180の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC |
Use at an assay dependent concentration.
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| ELISA |
Use at an assay dependent concentration.
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| WB |
Use at an assay dependent concentration.
|
| 特記事項 |
|---|
|
ICC
Use at an assay dependent concentration. |
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ELISA
Use at an assay dependent concentration. |
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WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. -
組織特異性
Plasma. -
関連疾患
Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. -
配列類似性
Belongs to the ALB/AFP/VDB family.
Contains 3 albumin domains. -
翻訳後修飾
Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 213 Human
- Omim: 103600 Human
- SwissProt: P02768 Human
- Unigene: 418167 Human
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別名
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab19180 は 5 報の論文で使用されています。
- Nakashima F et al. Structural and functional insights into S-thiolation of human serum albumins. Sci Rep 8:932 (2018). PubMed: 29343798
- Nehring J et al. Autoantibodies Against Albumin in Patients With Systemic Lupus Erythematosus. Front Immunol 9:2090 (2018). PubMed: 30333817
- Zheng Z et al. Hepatitis C virus mediated chronic inflammation and tumorigenesis in the humanised immune system and liver mouse model. PLoS One 12:e0184127 (2017). PubMed: 28886065
- Brandstätter H et al. Purification and biochemical characterization of functional complement factor H from human plasma fractions. Vox Sang 103:201-12 (2012). PubMed: 22497541
- Ding YD et al. A sandwich ELISA for assessment of pharmacokinetics of HSA-(BNP)2 fusion protein in mouse plasma. J Pharm Biomed Anal 51:658-63 (2010). ELISA . PubMed: 19836183