Anti-Human IgG3 抗体 [EPR4419] (ab109761)
![Western blot - Anti-Human IgG3 antibody [EPR4419] (ab109761)](https://www.abcam.co.jp/ps/products/109/ab109761/Images/ab109761-122772-anti-human-igg3-antibody-epr4419-western-blot.jpg "Western blot - Anti-Human IgG3 antibody [EPR4419] (ab109761)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4419] to Human IgG3
- Suitable for: WB, IP
- Reacts with: Human, Recombinant fragment
Related conjugates and formulations
製品の概要
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製品名
Anti-Human IgG3 antibody [EPR4419]
Human IgG3 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR4419] to Human IgG3 -
由来種
Rabbit -
特異性
ab109761 does not cross-react with human IgG1, IgG2, and IgG4. -
アプリケーション
適用あり: WB, IPmore details
適用なし: Flow Cyt,ICC/IF or IHC-P -
種交差性
交差種: Human, Recombinant fragment -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- IgG3 recombinant protein, Human tonsil and Human plasma lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR4419 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab109761の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000.
|
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| IP |
1/10 - 1/100.
|
| 特記事項 |
|---|
|
WB
1/1000 - 1/10000. |
|
IP
1/10 - 1/100. |
追加情報
Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
ターゲット情報
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関連性
IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 3502 Human
- Omim: 147120 Human
- SwissProt: P01860 Human
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別名
- DKFZp686H11213 antibody
- FLJ39988 antibody
- FLJ40036 antibody
see all
画像
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Western blot - Anti-Human IgG3 antibody [EPR4419] (ab109761)All lanes : Anti-Human IgG3 antibody [EPR4419] (ab109761) at 1/1000 dilution
Lane 1 : IgG3 at 0.01 µg
Lane 2 : IgG1 at 0.01 µg
Lane 3 : IgG2 at 0.01 µg
Lane 4 : IgG4 recombinant protein at 0.01 µg
Lane 5 : Human tonsil lysate at 10 µg
Lane 6 : Human plasma lysate -
![Anti-Human IgG3 antibody [EPR4419] (ab109761)](https://www.abcam.co.jp/ps/products/109/ab109761/Images/ab109761-2-benefits-of-recombinant-antibodies.png)
Anti-Human IgG3 antibody [EPR4419] (ab109761)
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab109761 は 11 報の論文で使用されています。
- Melani RD et al. Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire. J Proteome Res 21:274-288 (2022). PubMed: 34878788
- Zhang F et al. Hsa_circ_0010235 functions as an oncogenic drive in non-small cell lung cancer by modulating miR-433-3p/TIPRL axis. Cancer Cell Int 21:73 (2021). PubMed: 33494763
- Liu J et al. Circ_0105346 Knockdown Inhibits Osteosarcoma Development via Regulating miR-1182/WNT7B Axis. Cancer Manag Res 13:521-535 (2021). PubMed: 33505171
- Liu Y et al. MicroRNA-124 facilitates lens epithelial cell apoptosis by inhibiting SPRY2 and MMP-2. Mol Med Rep 23:N/A (2021). PubMed: 33760112
- Meng X et al. Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis. Front Oncol 11:652835 (2021). PubMed: 34141611