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AB34568

Anti-HSV1 + HSV2 抗体

Anti-HSV1 + HSV2 antibody

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(1 Publication)

Goat Polyclonal HSV1 antibody. Suitable for ELISA, ICC/IF and reacts with Herpes simplex virus, Human herpesvirus 2 samples. Cited in 1 publication. Immunogen corresponding to Virus preparation containing Human alphaherpesvirus 1 strain F protein.

別名を表示する

Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, Human Herpesvirus 1, Human herpesvirus type 1

Key facts

宿主種

Goat

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Herpes simplex virus, Human herpesvirus 2

アプリケーション

ELISA, ICC/IF

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

特異性

ab34568 recognises ICP's and late structural (virion) antigens. It does not recognise HepG2 cells.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Herpes simplex virus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Human herpesvirus 2": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製に関する特記事項
ab34568 is a purified IgG. Its purity state is >95%.
バッファー組成
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

HSV1 and HSV2 short for Herpes Simplex Virus Type 1 and Type 2 are double-stranded DNA viruses with similar structure and function. They are encapsulated with a lipid envelope featuring glycoproteins which are important for viral entry into host cells. These viruses have a capsid housing the viral genome and weigh around 150 kDa. HSV1 and HSV2 are primarily expressed in epithelial tissues and the nervous system specifically in neurons where they establish latency. HSV1 and HSV2 antibodies as well as anti-HSV1 antibodies and anti-HSV2 antibodies target these viruses aiding in research and diagnostics.
Biological function summary

HSV1 and HSV2 have significant roles in viral infection processes. They form complexes with host cell receptors to facilitate adhesion and entry into cells. Their glycoproteins interact with cellular proteins to trigger fusion and facilitate viral replication. During this process the viruses actively modulate the host's immune response enabling the evasion of immune detection. The ability to remain dormant and reactivate is an important aspect of their biology.

Pathways

HSV1 and HSV2 participate in cell entry and immune evasion processes. These viruses exploit the host's cellular machinery via the MAPK signaling pathway and the PI3K/Akt pathway to enhance viral replication and survival. The viral proteins ICP0 and glycoprotein D are essential for modulating these pathways. These interactions impact the immune response and cellular cycle regulation allowing the virus to maintain its presence within the host.

HSV1 and HSV2 are significant contributors to conditions like oral herpes and genital herpes. They are also associated with severe infections such as Herpes Simplex Encephalitis. The HSV1 and HSV2 target proteins through their interaction with host proteins facilitate these infections. Herpes Simplex Virus type-specific antibodies help in detecting and studying these viruses leading to better understanding and treatment of related conditions.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

See full target information HSV1

追加のターゲット

HSV2
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Phytochemistry 70:465-72 PubMed19272620

2009

Production and recovery of recombinant propapain with high yield.

Applications

Unspecified application

Species

Unspecified reactive species

Debi Choudhury,Sumana Roy,Chandana Chakrabarti,Sampa Biswas,J K Dattagupta
View all publications
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代替製品

Primary Antibodies

AB20922

HRP Anti-HSV1 + HSV2 antibody

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Primary Antibodies

AB226858

Anti-HSV1 + HSV2 antibody

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組合せ製品

Primary Antibodies

AB110227

Anti-HSV1 gH antibody [BBH1]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSV1 gH antibody [BBH1] (AB110227)

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  • 0
Primary Antibodies

AB6506

Anti-HSV1 + HSV2 gB antibody [10B7]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gB antibody [10B7] (AB6506)

  • 0
  • 0
Primary Antibodies

AB272686

Anti-VZV gE protein antibody [#9]

Western blot - Anti-VZV gE protein antibody [#9] (AB272686)

  • 0
  • 0
Primary Antibodies

AB6507

Anti-HSV1 + HSV2 gD antibody [2C10]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gD antibody [2C10] (AB6507)

  • 5
  • 1

Abcam product promise

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