JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB226858

Anti-HSV1 + HSV2 抗体

Anti-HSV1 + HSV2 antibody

Be the first to review this product! Submit a review

|

(3 Publications)

Rabbit Polyclonal HSV1 antibody. Suitable for WB and reacts with Herpes simplex virus, Human herpesvirus 2 samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing HSV1 protein.

別名を表示する

Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, Human Herpesvirus 1, Human herpesvirus type 1

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Herpes simplex virus, Human herpesvirus 2

アプリケーション

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

Virus preparation containing HSV2 protein.

特異性

ab226858 is specific for HSV1 and HSV2. It recognizes ICPs and late structural (virion) antigens.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Herpes simplex virus": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Human herpesvirus 2": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
style
left-column

製品の詳細

Concentration is typically 4-5 mg/ml.
style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製に関する特記事項
Purity >95%
バッファー組成
pH: 7.2 Preservative: 0.1% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
style
left-column

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

HSV1 and HSV2 short for Herpes Simplex Virus Type 1 and Type 2 are double-stranded DNA viruses with similar structure and function. They are encapsulated with a lipid envelope featuring glycoproteins which are important for viral entry into host cells. These viruses have a capsid housing the viral genome and weigh around 150 kDa. HSV1 and HSV2 are primarily expressed in epithelial tissues and the nervous system specifically in neurons where they establish latency. HSV1 and HSV2 antibodies as well as anti-HSV1 antibodies and anti-HSV2 antibodies target these viruses aiding in research and diagnostics.
Biological function summary

HSV1 and HSV2 have significant roles in viral infection processes. They form complexes with host cell receptors to facilitate adhesion and entry into cells. Their glycoproteins interact with cellular proteins to trigger fusion and facilitate viral replication. During this process the viruses actively modulate the host's immune response enabling the evasion of immune detection. The ability to remain dormant and reactivate is an important aspect of their biology.

Pathways

HSV1 and HSV2 participate in cell entry and immune evasion processes. These viruses exploit the host's cellular machinery via the MAPK signaling pathway and the PI3K/Akt pathway to enhance viral replication and survival. The viral proteins ICP0 and glycoprotein D are essential for modulating these pathways. These interactions impact the immune response and cellular cycle regulation allowing the virus to maintain its presence within the host.

HSV1 and HSV2 are significant contributors to conditions like oral herpes and genital herpes. They are also associated with severe infections such as Herpes Simplex Encephalitis. The HSV1 and HSV2 target proteins through their interaction with host proteins facilitate these infections. Herpes Simplex Virus type-specific antibodies help in detecting and studying these viruses leading to better understanding and treatment of related conditions.
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

See full target information HSV1

追加のターゲット

HSV2
style
left-column

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Neoplasia (New York, N.Y.) 63:101152 PubMed40096771

2025

Targeting BARD1 suppresses a Myc-dependent transcriptional program and tumor growth in pancreatic ductal adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Sohum Patel,Eleanor Jenkins,Rutuj P Kusurkar,Sherry Lee,Wei Jiang,Avinoam Nevler,Matthew McCoy,Michael J Pishvaian,Rosalie C Sears,Jonathan R Brody,Charles J Yeo,Aditi Jain

Proceedings of the National Academy of Sciences of the United States of America 118: PubMed34417304

2021

A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Katherine Kaugars,Joseph Dardick,Anna Paula de Oliveira,Kayla A Weiss,Regy Lukose,John Kim,Lawrence Leung,Saranathan Rajagopalan,Sydney Wolin,Leor Akabas,David M Knipe,Goran Bajic,William R Jacobs

Molecular therapy oncolytics 20:220-227 PubMed33665360

2021

Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Gaku Takano,Shinichi Esaki,Fumi Goshima,Atsushi Enomoto,Yoshimi Hatano,Haruka Ozaki,Takahiro Watanabe,Yoshitaka Sato,Daisuke Kawakita,Shingo Murakami,Takayuki Murata,Yukihiro Nishiyama,Shinichi Iwasaki,Hiroshi Kimura
View all publications
style
left-column
style
left-column
style
right-column

代替製品

Primary Antibodies

AB20922

HRP Anti-HSV1 + HSV2 antibody

  • 0
  • 0
Primary Antibodies

AB34568

Anti-HSV1 + HSV2 antibody

  • 0
  • 0

組合せ製品

Primary Antibodies

AB110227

Anti-HSV1 gH antibody [BBH1]

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSV1 gH antibody [BBH1] (AB110227)

  • 0
  • 0
Primary Antibodies

AB6506

Anti-HSV1 + HSV2 gB antibody [10B7]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gB antibody [10B7] (AB6506)

  • 0
  • 0
Primary Antibodies

AB272686

Anti-VZV gE protein antibody [#9]

Western blot - Anti-VZV gE protein antibody [#9] (AB272686)

  • 0
  • 0
Primary Antibodies

AB6507

Anti-HSV1 + HSV2 gD antibody [2C10]

Immunocytochemistry/ Immunofluorescence - Anti-HSV1 + HSV2 gD antibody [2C10] (AB6507)

  • 5
  • 1

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com