Anti-Hsd17b11 抗体 (ab167686)
Key features and details
- Mouse polyclonal to Hsd17b11
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
製品の概要
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製品名
Anti-Hsd17b11 antibody
Hsd17b11 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to Hsd17b11 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Recombinant fragment
交差が予測される動物種: Chimpanzee, Rhesus monkey, Common marmoset, Orangutan
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免疫原
Recombinant full length protein within Human Hsd17b11 aa 1-300. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ･コントロール
- Hsd17b11 transfected 293T cell line lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab167686の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 33 kDa.
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Predicted molecular weight: 33 kDa. |
ターゲット情報
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機能
Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. -
組織特異性
Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart. -
配列類似性
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 461364 Chimpanzee
- Entrez Gene: 100174773 Orangutan
- SwissProt: Q5NVG2 Orangutan
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別名
- 17 beta HSD 11 antibody
- 17 beta HSD XI antibody
- 17 BETA HSD11 antibody
see all
画像
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Western blot - Anti-Hsd17b11 antibody (ab167686)All lanes : Anti-Hsd17b11 antibody (ab167686) at 1/500 dilution
Lane 1 : Hsd17b11 transfected 293T cell line lysate
Lane 2 : Non-transfected 293T cell line lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Mouse IgG at 1/5000 dilution
Predicted band size: 33 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab167686 は 1 報の論文で使用されています。
- Tang BX et al. Ziyin Bushen Decoction Alleviates Perimenopausal Syndrome in Rats by Enhancing Estradiol Production. Evid Based Complement Alternat Med 2020:8895809 (2020). PubMed: 33204296
