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AB20944

HRP Anti-Rubella Virions 抗体

HRP Anti-Rubella Virions antibody

  • JP Deleterious:医薬用外劇物

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(1 Publication)

Goat Polyclonal Rubella Virions antibody - conjugated to HRP. Suitable for ICC and reacts with Rubella virus samples. Cited in 1 publication.

Key facts

宿主種

Goat

クローン性

Polyclonal

アイソタイプ

IgG

標識

HRP

励起波長/蛍光波長
キャリアフリー

No

交差種

Rubella virus

アプリケーション

ICC

applications

特異性

Purified virions. Negative against Vero cells by indirect immunofluorescence.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rubella virus": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>" } } }

製品の詳細

Covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed. Estimated molar HRP:IgG substitution is 2-3. Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
Preservative: 0.002% Thimerosal (merthiolate) Constituents: PBS, 1% BSA
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Rubella virions also known as rubella virus particles are spherical and enveloped entities with an average diameter of 50-70 nm. These virions are composed mainly of three structural proteins: the capsid protein and the envelope glycoproteins E1 and E2. Within the host cell rubella virions replicate in the cytoplasm of infected epithelial cells. Their envelope derives from the host cell membrane highlighting their interaction with the infected host during budding.
Biological function summary

Rubella virions serve as the infectious agents responsible for the transmission of rubella which is a contagious disease characterized by rash and fever. As individual units rubella virions do not form part of a complex with other viruses but require assembly via interactions among the capsid protein and envelope glycoproteins. The virion structure plays a central role in facilitating host cell receptor binding and membrane fusion which allows the virus to deliver its RNA genome into host cells for replication.

Pathways

Viral entry and replication mechanisms drive the activities of rubella virions. The virions exploit the endocytic pathway to enter host cells a process that is important for initiating infection. During replication non-structural proteins facilitate the synthesis of viral components. Important proteins in these processes include the E1 glycoprotein which is involved in receptor interaction and membrane fusion an integral part of the virion's infection cycle.

Rubella virions are primarily linked to rubella infection also known as German measles and congenital rubella syndrome. This viral infection triggers an immune response in the host involving cytokines and antibodies notably the anti-rubella antibody which helps clear the virus. Congenital rubella syndrome occurs when maternal infection during pregnancy results in significant developmental anomalies in the fetus. This association highlights the importance of monitoring and vaccination efforts to prevent these serious conditions.

製品プロトコール

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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Autophagy 21:407-423 PubMed39291751

2024

Serine ubiquitination of SQSTM1 regulates NFE2L2-dependent redox homeostasis.

Applications

Unspecified application

Species

Unspecified reactive species

Rukmini Mukherjee,Anshu Bhattacharya,João Mello-Vieira,Santosh Kumar Kuncha,Marina Hoffmann,Alexis Gonzalez,Rajeshwari Rathore,Attinder Chadha,Donghyuk Shin,Thomas Colby,Ivan Matic,Shaeri Mukherjee,Mohit Misra,Ivan Dikic
View all publications

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