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HRP Anti-HIV1 gp41 抗体 (ab68622)

Submit a review Q&A (1)References (1)

Key features and details

  • HRP Goat polyclonal to HIV1 gp41
  • Suitable for: WB, ELISA
  • Reacts with: Human immunodeficiency virus
  • Conjugation: HRP
  • Isotype: IgG

製品の概要

  • 製品名

    HRP Anti-HIV1 gp41 antibody
    HIV1 gp41 一次抗体 製品一覧

  • 製品の詳細

    HRP Goat polyclonal to HIV1 gp41

  • 由来種

    Goat

  • 標識

    HRP

  • 特異性

    This antibody reacts with HIV1 gp41 in viral and infected tissue samples.

  • アプリケーション

    適用あり: WB, ELISAmore details

  • 種交差性

    交差種: Human immunodeficiency virus

  • 免疫原

    Recombinant fragment, corresponding to the ectodomain of gp41-glycosylated (a.a. residues 546-682) from strain HxB2.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab68622の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa.
ELISA
1/200 - 1/1000.
特記事項
WB
Use at an assay dependent concentration. Predicted molecular weight: 41 kDa.
ELISA
1/200 - 1/1000.

ターゲット情報

  • 関連性

    gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

  • 参照データベース

    • 別名

      • Env antibody
      • Glycoprotein 41 antibody
      • gp41 antibody
      • Human Immunodeficiency Virus 1 antibody
      • TM antibody
      • Transmembrane protein antibody
      see all

    参考文献 (1)

    ab68622 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab68622 は 1 報の論文で使用されています。

    • Zhou X  et al. Alpha-1-antitrypsin interacts with gp41 to block HIV-1 entry into CD4+ T lymphocytes. BMC Microbiol 16:172 (2016). WB ; Human . PubMed: 27473095

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    Hello,

    We would like to immobilize Anti-HIV1 gp120 onto a surface to show efficacy in capturing HIV protein.

    Our current thought is to:
    1. Immobilize Anti-HIV1 gp120 antibody (Product # ab21179)
    2.Capture HIV1 gp120 + gp41 protein (Product #ab68127)
    3. Use the secondary protein, Anti-HIV1 gp41 (Product # ab68622) conjugated to HRP to measure and quantify the amount of captured protein.

    Can you confirm that the three products (ab21179, ab68127, and ab68622) will interact as predicted?

    Read More
    Answer

    Thank you for contacting us. Theoretically your outline makes sense. However, we have not tested the products this way and cannot guarantee that the binding sites of the antibodies will not interfere with each other. I hope this is helpful. Please le me know if I can be of further assistance.

    Read More

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