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HRP Anti-Endostatin/COL18A1 抗体 [KT60] (ab106491)

Submit a review Q&A (1)
Sandwich ELISA - HRP Anti-Endostatin/COL18A1 antibody [KT60] (ab106491)

    Key features and details

    • HRP Mouse monoclonal [KT60] to Endostatin/COL18A1
    • Suitable for: Sandwich ELISA
    • Reacts with: Human
    • Conjugation: HRP
    • Isotype: IgG2a

    製品の概要

    • 製品名

      HRP Anti-Endostatin/COL18A1 antibody [KT60]
      Endostatin/COL18A1 一次抗体 製品一覧

    • 製品の詳細

      HRP Mouse monoclonal [KT60] to Endostatin/COL18A1

    • 由来種

      Mouse

    • 標識

      HRP

    • アプリケーション

      適用あり: Sandwich ELISAmore details

    • 種交差性

      交差種: Human

    • 免疫原

      Recombinant full length protein corresponding to Human Endostatin/COL18A1 (N terminal).

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab106491の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    Sandwich ELISA
    1/1000. Can be paired for Sandwich ELISA with Mouse monoclonal [KT58] to Endostatin/COL18A1 (ab114141).
    特記事項
    Sandwich ELISA
    1/1000. Can be paired for Sandwich ELISA with Mouse monoclonal [KT58] to Endostatin/COL18A1 (ab114141).

    ターゲット情報

    • 機能

      COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.
      Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

    • 組織特異性

      Present in multiple organs with highest levels in liver, lung and kidney.

    • 関連疾患

      Defects in COL18A1 are a cause of Knobloch syndrome (KNO) [MIM:267750]. KNO is an autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele.

    • 配列類似性

      Belongs to the multiplexin collagen family.
      Contains 1 FZ (frizzled) domain.
      Contains 1 TSP N-terminal (TSPN) domain.

    • 翻訳後修飾

      Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.

    • 細胞内局在

      Secreted > extracellular space > extracellular matrix.
    • Information by UniProt

    • 参照データベース

      • 別名

        • Alpha 1 collagen type 18 (XVIII)(COL18A1) antibody
        • Alpha 1 type XVIII collagen antibody
        • Antiangiogenic agent antibody
        • COIA1_HUMAN antibody
        • COL15A1 antibody
        • Col18a1 antibody
        • Collagen alpha 1(XV) chain antibody
        • Collagen alpha 1(XVIII) chain antibody
        • Collagen alpha-1(XV) chain antibody
        • Collagen type XV proteoglycan antibody
        • Collagen type XVIII alpha 1 antibody
        • Collagen XV, alpha 1 polypeptide antibody
        • Collagen, type XV, alpha 1 antibody
        • Endostatin antibody
        • Endostatin XV antibody
        • FLJ27325 antibody
        • FLJ34914 antibody
        • FLJ38566 antibody
        • KNO antibody
        • KNO1 antibody
        • KS antibody
        • MGC74745 antibody
        • Multi functional protein MFP antibody
        • OTTHUMP00000021782 antibody
        • OTTHUMP00000115472 antibody
        • OTTHUMP00000115473 antibody
        see all

      画像

      • Sandwich ELISA - HRP Anti-Endostatin/COL18A1 antibody [KT60] (ab106491)
        Sandwich ELISA - HRP Anti-Endostatin/COL18A1 antibody [KT60] (ab106491)

        ab106491 at 1/1000 dilution detecting Endostatin/COL18A1 by sandwich ELISA. The capture antibody is a mouse monclonal (IgG1) raised against Human Endostatin/COL18A1.

      プロトコール

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      参考文献 (0)

      ab106491 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab106491 は論文での使用が確認できていません。

      レビューと Q&A

      Show All レビュー Q&A
      レビューを送る 質問を送る

      Question

      Could you let me know the cataloge number of pair antibody for Sandwich ELISA?

      Read More
      Answer

      I am very sorry for the delayed answer. I can now confirm that ab106491 has been tested and is guaranteed to work with ab114141 as an sandwich ELISA pair. The datasheet for ab114141 can be found following this link: Click here (or use the following: https://www.abcam.com/EndostatinCOL18A1-antibody-KT58-ab114141.html). I hope this information was helpful. Please do not hesitate to contact me again with any further questions.

      Read More

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