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AB112976

HRP Anti-Albumin 抗体

HRP Anti-Albumin antibody

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(1 Publication)

Sheep Polyclonal Albumin antibody - conjugated to HRP. Suitable for ICC, ELISA, WB, IHC-P and reacts with Horse samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human ALB.

別名を表示する

GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, ALB, Albumin

Key facts

宿主種

Sheep

クローン性

Polyclonal

アイソタイプ

IgG

標識

HRP

励起波長/蛍光波長
キャリアフリー

No

交差種

Horse

アプリケーション

ELISA, ICC, WB, IHC-P

applications

免疫原

Native Full Length Protein corresponding to Human ALB.

P02768

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Horse": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>Colorimetric: Use 1/1000-1/10000 dilution; Chemiluminescent: Use 1/1000-1/30000 dilution.</p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
Antiserum was solid phase adsorbed to ensure class specificity. ab112976 was isolated by affinity chromatography using antigen coupled to agarose beads.
バッファー組成
pH: 6.8 - 7.4 Preservative: 0.05% CMIT/MIT based preservative Constituents: 0.2% BSA
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Albumin also known as ALB is a major plasma protein with a molecular mass of approximately 66.5 kDa. It predominantly gets synthesized in the liver and found abundantly in blood plasma. Albumin serves multiple functions including maintaining osmotic pressure and acting as a carrier protein for various endogenous substances like hormones fatty acids and bilirubin.
Biological function summary

Albumin plays a critical role in transporting small molecules like metabolites and drugs through the circulatory system. It is not a part of any complex but functions independently to bind transport and release various ligands. Albumin's affinity for hydrophobic molecules makes it essential for they to be solubilized in blood for proper metabolism and excretion.

Pathways

More than five binding sites on albumin facilitate its role in the fatty acid metabolism and renin-angiotensin system pathways. In fatty acid metabolism albumin interacts with transport proteins carrying fatty acids to tissues for energy production. Additionally during the renin-angiotensin system albumin modulates blood pressure through its interaction with angiotensin II which can influence vasoconstriction.

Researchers link albumin with nephrotic syndrome and liver cirrhosis. In nephrotic syndrome low levels of albumin (albumin low) can cause edema due to imbalanced osmotic pressure. In liver cirrhosis a reduction in albumin synthesis signifies liver damage. Albumin's interaction with proteins like angiotensin II correlates with complications such as hypertension further establishing the protein's role in health and disease contexts.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs (Probable). Its main function is the regulation of the colloidal osmotic pressure of blood (Probable). Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (PubMed : 19021548). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed : 6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed : 6234017).
See full target information ALB
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Alimentary pharmacology & therapeutics 53:410-417 PubMed33264440

2020

Mucosal penetration and clearance of gluten and milk antigens in eosinophilic oesophagitis.

Applications

Unspecified application

Species

Unspecified reactive species

Anupama Ravi,Eric V Marietta,Jeffrey A Alexander,Kathryn Peterson,Crystal Lavey,Debra M Geno,Joseph A Murray,David A Katzka
View all publications
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代替製品

Primary Antibodies

AB137885

Anti-Albumin antibody [EPSISR1]

RabMAb|Recombinant|KO Validated|Lab Essentials

Western blot - Anti-Albumin antibody [EPSISR1] (AB137885)

  • 0
  • 0
Primary Antibodies

AB175934

Anti-Albumin antibody [EPR12780(B)]

RabMAb|Recombinant|Lab Essentials

Western blot - Anti-Albumin antibody [EPR12780(B)] (AB175934)

  • 0
  • 0
Primary Antibodies

AB151742

Anti-Albumin antibody [EPSISR3]

RabMAb|Recombinant|Lab Essentials

Western blot - Anti-Albumin antibody [EPSISR3] (AB151742)

  • 0
  • 0
Primary Antibodies

AB240109

Anti-Albumin antibody [EPSISR1] - BSA and Azide free

RabMAb|Recombinant

Western blot - Anti-Albumin antibody [EPSISR1] - BSA and Azide free (AB240109)

  • 0
  • 0
Primary Antibodies

AB207327

Anti-Albumin antibody [EPR20195]

RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Albumin antibody [EPR20195] (AB207327)

  • 5
  • 2
Primary Antibodies

AB222923

Anti-Albumin antibody [EPR20195] - Low endotoxin, Azide free

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Albumin antibody [EPR20195] - Low endotoxin, Azide free (AB222923)

  • 0
  • 0

組合せ製品

Assay Kits

AB235628

Albumin (BCG) Assay Kit (Colorimetric)

Functional Studies - Albumin (BCG) Assay Kit (Colorimetric) (AB235628)

  • 0
  • 0
Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

  • 5
  • 15
Primary Antibodies

AB191338

HRP Anti-Streptavidin antibody

  • 0
  • 0
Assay Kits

AB179887

Human Albumin ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human Albumin ELISA Kit (AB179887)

  • 3
  • 1
Primary Antibodies

AB37382

Chicken IgY, polyclonal - Isotype Control (BSA and Azide free)

  • 0
  • 0

Abcam product promise

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