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AB20190

Anti-HPV16 E1+E4 抗体 [TVG 403]

Anti-HPV16 E1+E4 antibody [TVG 403]

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(1 Publication)

Mouse Monoclonal VE1 antibody. Suitable for Flow Cyt, ELISA, IHC-Fr and reacts with Human papillomavirus type 16 samples. Cited in 1 publication. Immunogen corresponding to Recombinant Protein within Human papillomavirus type 16 E1.

別名を表示する

Replication protein E1, ATP-dependent helicase E1, E1

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

TVG 403

アイソタイプ

IgG1

キャリアフリー

No

交差種

Human papillomavirus type 16

アプリケーション

ELISA, Flow Cyt, IHC-Fr

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

Recombinant Protein within Human papillomavirus type 16 E4. Database link P06922

エピトープ

E1/E4 protein is aa 36-41 of human papilloma virus type 16.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human papillomavirus type 16": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p><a href='/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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製品の詳細

This antibody is of value in monitoring the progress of HPV infection from benign lesions to invasive cancer.
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A/G
バッファー組成
Preservative: 0.02% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins. During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity. Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer. Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori. Subsequently, two hexamers will be created. The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
See full target information E1
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of virology 74:10081-95 PubMed11024137

2000

The E1E4 protein of human papillomavirus type 16 associates with a putative RNA helicase through sequences in its C terminus.

Applications

Unspecified application

Species

Unspecified reactive species

J Doorbar,R C Elston,S Napthine,K Raj,E Medcalf,D Jackson,N Coleman,H M Griffin,P Masterson,S Stacey,Y Mengistu,J Dunlop
View all publications
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代替製品

Primary Antibodies

AB270738

Anti-HPV16 E1+E4 antibody [HPV16 E1/E4]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 E1+E4 antibody [HPV16 E1/E4] (AB270738)

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組合せ製品

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AB267404

Anti-HPV18 L1 antibody

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Primary Antibodies

AB977

Anti-E2 tag antibody [5E11]

Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-E2 tag antibody [5E11] (AB977)

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Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

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Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [EPR24852-116] - BSA and Azide free

RabMAb|Recombinant

Flow Cytometry - Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [EPR24852-116] - BSA and Azide free (AB283943)

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Abcam product promise

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保証に関する詳細については利用規約をご確認ください。

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