Anti-HOXC10 抗体 (ab153904)
Key features and details
- Rabbit polyclonal to HOXC10
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-HOXC10 antibody
HOXC10 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HOXC10 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment corresponding to Human HOXC10 aa 16-312.
Database link: Q9NYD6 -
ポジティブ･コントロール
- HeLa, HepG2, Mouse muscle whole cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153904の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 38 kDa.
|
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| IHC-P | (1) |
1/100 - 1/1000.
|
| ICC/IF | (1) |
1/100 - 1/1000.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 38 kDa. |
|
IHC-P
1/100 - 1/1000. |
|
ICC/IF
1/100 - 1/1000. |
ターゲット情報
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機能
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. -
配列類似性
Belongs to the Abd-B homeobox family.
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 3226 Human
- Entrez Gene: 209448 Mouse
- Omim: 605560 Human
- SwissProt: Q9NYD6 Human
- SwissProt: P31257 Mouse
- Unigene: 44276 Human
- Unigene: 31665 Mouse
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別名
- Hmeobox protein Hox C10 antibody
- Homeobox Protein Hox C10 antibody
- Homeobox protein Hox-3I antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-HOXC10 antibody (ab153904)
Immunofluorescent analysis of paraformaldehyde-fixed HeLa cells labeling HOXC10 with ab153904 at 1/2000 dilution. Alpha tubulin filaments were labeled red.
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Western blot - Anti-HOXC10 antibody (ab153904)All lanes : Anti-HOXC10 antibody (ab153904) at 1/1000 dilution
Lane 1 : HeLa whole cell lysate
Lane 2 : HepG2 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 38 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HOXC10 antibody (ab153904)Immunohistochemical analysis of paraffin-embedded HeLa xenograft tissue labeling HOXC10 with ab153904 at 1/500 dilution.
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Western blot - Anti-HOXC10 antibody (ab153904)Anti-HOXC10 antibody (ab153904) at 1/1000 dilution + Mouse muscle lysate at 50 µg
Predicted band size: 38 kDa
10% SDS PAGE
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (22)
ab153904 は 22 報の論文で使用されています。
- Zhou Y et al. m6A‑modified HOXC10 promotes HNSCC progression via co‑activation of ADAM17/EGFR and Wnt/β‑catenin signaling. Int J Oncol 64:N/A (2024). PubMed: 38063205
- He X et al. HOXC10 promotes esophageal squamous cell carcinoma progression by targeting FOXA3 and indicates poor survival outcome. Heliyon 9:e21056 (2023). PubMed: 37876483
- Xi Y et al. Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma. Signal Transduct Target Ther 7:53 (2022). PubMed: 35210398
- Wu K et al. MiR-4739 inhibits the malignant behavior of esophageal squamous cell carcinoma cells via the homeobox C10/vascular endothelial growth factor A/phosphatidylinositol 3-kinase/AKT pathway. Bioengineered 13:14066-14079 (2022). PubMed: 35730500
- Yu J et al. HOXC10 Promotes Metastasis in Colorectal Cancer by Recruiting Myeloid-derived Suppressor Cells. J Cancer 13:3308-3317 (2022). PubMed: 36186898