Anti-HLA G 抗体 [MEM-G/9] (ab7758)
![Flow Cytometry - Anti-HLA G antibody [MEM-G/9] (ab7758)](https://www.abcam.co.jp/ps/products/7/ab7758/Images/ab7758-521320-anti-hla-g-antibody-mem-g-9-flow-cytometry-transfected-lcl-cells-human.jpg "Flow Cytometry - Anti-HLA G antibody [MEM-G/9] (ab7758)")
Key features and details
- Mouse monoclonal [MEM-G/9] to HLA G
- Suitable for: Flow Cyt
- Reacts with: Human
- Isotype: IgG1
Related conjugates and formulations
製品の概要
-
製品名
Anti-HLA G antibody [MEM-G/9]
HLA G 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MEM-G/9] to HLA G -
由来種
Mouse -
特異性
Reacts with the native form of human HLA-G on the cell surface as well as with soluble HLA-G molecule in its beta 2-microglobulin associated form. Specificity was demonstrated with cells transfected with either full-length HLA-G and HLA-G1 complementary DNA. This antibody does not compete with a tested panel of other monoclonal antibodies to HLA-G. We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human
非交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Human HLA G.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
MEM-G/9 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Alternative Versions
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
-
Recombinant Protein
-
Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab7758の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | (1) |
Use at an assay dependent concentration.
Do not fix cells, see Menier et al. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Do not fix cells, see Menier et al. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells. -
組織特異性
Expressed in trophoblasts. -
配列類似性
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 3135 Human
- Omim: 142871 Human
- SwissProt: P17693 Human
- Unigene: 512152 Human
-
別名
- B2 microglobulin antibody
- DADB-15K14.8 antibody
- HLA 6.0 antibody
see all
画像
-
Flow Cytometry - Anti-HLA G antibody [MEM-G/9] (ab7758)
Flow cytometry analysis showing separation of HLA-G trasnfected LCL cells (red-filled) from K562 cells (black-dashed) stained using ab7758 (concentration in sample 0.3 μg/ml, GAM APC).
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (30)
ab7758 は 30 報の論文で使用されています。
- Wang LJ et al. Functional antagonism between ΔNp63α and GCM1 regulates human trophoblast stemness and differentiation. Nat Commun 13:1626 (2022). PubMed: 35338152
- Tan JP et al. Establishment of human induced trophoblast stem cells via reprogramming of fibroblasts. Nat Protoc 17:2739-2759 (2022). PubMed: 36241724
- Wu H et al. Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing. Front Bioeng Biotechnol 9:690409 (2021). PubMed: 34631675
- Sato M et al. Three-dimensional human placenta-like bud synthesized from induced pluripotent stem cells. Sci Rep 11:14167 (2021). PubMed: 34239021
- Tang L et al. Deficiency of DICER reduces the invasion ability of trophoblasts and impairs the pro-angiogenic effect of trophoblast-derived microvesicles. J Cell Mol Med 24:4915-4930 (2020). PubMed: 32198822