Anti-HIV2 gp36 抗体 [3B10/G2] (ab18628)
Key features and details
- Mouse monoclonal [3B10/G2] to HIV2 gp36
- Suitable for: ELISA, WB
- Reacts with: HIV-2
- Isotype: IgG2a
製品の概要
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製品名
Anti-HIV2 gp36 antibody [3B10/G2] -
製品の詳細
Mouse monoclonal [3B10/G2] to HIV2 gp36 -
由来種
Mouse -
アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: HIV-2 -
免疫原
HIV2 recombinant antigen 00114-V.
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エピトープ
Recognition epitope resides between amino acid residues 390a.a.-702 a.a. of HIV gp36 antigen. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
3B10/G2 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab18628の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
1/500.
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WB |
1/1000. Predicted molecular weight: 34 kDa.
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特記事項 |
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ELISA
1/500. |
WB
1/1000. Predicted molecular weight: 34 kDa. |
ターゲット情報
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関連性
HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection. -
別名
- Gp36 antibody
- HIV 2 antibody
- Human immunodeficiency virus 2 antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab18628 は論文での使用が確認できていません。