Anti-HIV1 p24 抗体 (ab63913)
Key features and details
- Rabbit polyclonal to HIV1 p24
- Suitable for: WB, ELISA
- Reacts with: Human immunodeficiency virus
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-HIV1 p24 antibody
HIV1 p24 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HIV1 p24 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Human immunodeficiency virus -
免疫原
Recombinant p24 protein over-expressed in E.coli using a plasmid carrying the Gag p24 coding region of HIV1 virus, subtype B.
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ポジティブ･コントロール
- Extract of MT4 cells infected with HIV-1 (LAI strain).
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 6
Preservative: 0.09% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63913の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/2500. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa).
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| ELISA |
Use at an assay dependent dilution.
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| 特記事項 |
|---|
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WB
1/2500. Detects a band of approximately 24 kDa (predicted molecular weight: 24 kDa). |
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ELISA
Use at an assay dependent dilution. |
ターゲット情報
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関連性
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
細胞内局在
Membrane -
参照データベース
- SwissProt: P04585 Human immunodeficiency virus
- SwissProt: P12497 Human immunodeficiency virus
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別名
- CA antibody
- Capsid protein p24 antibody
- HIV-1 Gag p24 antibody
see all
画像
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Western blot - Anti-HIV1 p24 antibody (ab63913)All lanes : Anti-HIV1 p24 antibody (ab63913) at 1/2500 dilution
Lane 1 : Extract of MT4 cells
Lane 2 : Extract of MT4 cells infected with HIV-1 (LAI strain)
Predicted band size: 24 kDa
Observed band size: 24 kDa
Bands at 41 and 55 kDa are also observed corresponding to HIV-p24 precursor proteins p41 and p55.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (23)
ab63913 は 23 報の論文で使用されています。
- Pang H et al. Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane. Proc Natl Acad Sci U S A 120:e2212991120 (2023). PubMed: 36638209
- Wang S et al. Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity. Proc Natl Acad Sci U S A 119:N/A (2022). PubMed: 34987100
- Munoz O et al. Active PD-L1 incorporation within HIV virions functionally impairs T follicular helper cells. PLoS Pathog 18:e1010673 (2022). PubMed: 35788752
- Zhao L et al. Vpr counteracts the restriction of LAPTM5 to promote HIV-1 infection in macrophages. Nat Commun 12:3691 (2021). PubMed: 34140527
- Meuser ME et al. Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type-1 Capsid Inhibitor Using a Multistep Computational Workflow. J Med Chem 64:3747-3766 (2021). PubMed: 33750123