Anti-HIV1 p15 抗体 (ab66951)
Key features and details
- Rabbit polyclonal to HIV1 p15
- Suitable for: WB, ELISA
- Reacts with: Human immunodeficiency virus
- Isotype: IgG
製品の概要
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製品名
Anti-HIV1 p15 antibody -
製品の詳細
Rabbit polyclonal to HIV1 p15 -
由来種
Rabbit -
アプリケーション
適用あり: WB, ELISAmore details -
種交差性
交差種: Human immunodeficiency virus -
免疫原
Recombinant p15 protein (HIV1) expressed in E.coli with a plasmid carrying the Gag p15 coding region of HIV1 virus.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 6
Preservative: 0.09% Sodium azide
Constituent: Whole serum -
Concentration information loading... -
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab66951の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000. Detects a band of approximately 15 kDa (predicted molecular weight: 15 kDa).
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| ELISA |
Use at an assay dependent dilution.
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| 特記事項 |
|---|
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WB
1/1000. Detects a band of approximately 15 kDa (predicted molecular weight: 15 kDa). |
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ELISA
Use at an assay dependent dilution. |
ターゲット情報
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関連性
HIV1 p15(Gag) and its protease cleavage products, nucleocapsid protein p7 and p6, are believed to play a major role in viral infectivity and assembly during the early and late stages of retroviral life cycle. p15 is frequently recognized by HIV1-specific CD8+T cells in natural HIV1 infection and may be an important target for the design of future HIV1 vaccines. -
細胞内局在
Cytoplasmic and Nuclear -
参照データベース
- Entrez Gene: 155030 Human immunodeficiency virus
- SwissProt: P03366 Human immunodeficiency virus
- SwissProt: P04591 Human immunodeficiency virus
- SwissProt: P18802 Human immunodeficiency virus
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別名
- gag antibody
- Gag polyprotein antibody
- Human Immunodeficiency virus 1 antibody
see all
画像
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Western blot - Anti-HIV1 p15 antibody (ab66951)All lanes : Anti-HIV1 p15 antibody (ab66951) at 1/1000 dilution
Lane 1 : Molecular weight markers
Lane 2 : Extract of MT4 cells
Lane 3 : Extract of MT4 cells infected with HIV1
(LAI strain)
Predicted band size: 15 kDa
Observed band size: 15 kDa
Additional bands at: 55 kDa. We are unsure as to the identity of these extra bands.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab66951 は 4 報の論文で使用されています。
- Tarrés-Freixas F et al. An engineered HIV-1 Gag-based VLP displaying high antigen density induces strong antibody-dependent functional immune responses. NPJ Vaccines 8:51 (2023). PubMed: 37024469
- Lu B et al. Delivering SaCas9 mRNA by lentivirus-like bionanoparticles for transient expression and efficient genome editing. Nucleic Acids Res N/A:N/A (2019). PubMed: 30759231
- Lyu P et al. Delivering Cas9/sgRNA ribonucleoprotein (RNP) by lentiviral capsid-based bionanoparticles for efficient 'hit-and-run' genome editing. Nucleic Acids Res 47:e99 (2019). PubMed: 31299082
- Garcia-Miranda P et al. Stability of HIV Frameshift Site RNA Correlates with Frameshift Efficiency and Decreased Virus Infectivity. J Virol 90:6906-17 (2016). PubMed: 27194769