Anti-Hepatitis B Virus Core Antigen 抗体 [C1]
Anti-Hepatitis B Virus Core Antigen antibody [C1]
4
(1 Review)
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(33 Publications)
Anti-Hepatitis B Virus Core Antigen antibody [C1] (ab8637) is a mouse monoclonal antibody detecting Hepatitis B Virus Core Antigen in Western Blot, IP, ICC/IF, ELISA. Suitable for Hepatitis B virus.
- Over 20 publications
- Trusted since 2002
別名を表示する
Capsid Protein, Core and e antigen, Core antigen, Core protein, HBVgp4, HBc, HBcAg, Hepatitis B Virus core antigen, Hepatitis B core antigen, p21.5, precore/core protein
- WB
Unknown
Western blot - Anti-Hepatitis B Virus Core Antigen antibody [C1] (AB8637)
Immunoblotting analysis of the recombinant HBcAg antigen using ab8637. E.coli lysates were separated using 12% SDS-PAAG electrophoresis, imunoblotted and developed with the Amersham ECL Detection Kit. Samples : 1. Negative control; 2. HBcAg (full length, 1-183)
All lanes:
Western blot - Anti-Hepatitis B Virus Core Antigen antibody [C1] (ab8637)
Predicted band size: 21 kDa
false
Reactivity data
製品の詳細
Anti-Hepatitis B Virus Core Antigen antibody [C1] (ab8637) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Hepatitis B virus samples.
Trusted by the scientific community
Anti-Hepatitis B Virus Core Antigen [C1] (ab8637) was first used in a scientific publication in 2002 and has been cited over 20 times in peer-reviewed journals.
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補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The hepatitis B core antigen is integral for the assembly of the viral capsid which protects the viral genome during infection. It functions as part of a larger complex with other viral proteins including the pre-core and envelope proteins to facilitate viral lifecycle processes. This antigen allows for the encapsidation of viral RNA and serves as a scaffold for reverse transcription of the viral genome ensuring replication fidelity and successful infection spread.
Pathways
The hepatitis B core antigen is essential in the viral replication pathway and the HBV lifecycle pathway. It interacts closely with HBV polymerase during the packaging of viral genome into the capsid. These interactions are important for the transformation of RNA into DNA a critical step in viral maturation. The antigen is related to the HBx protein through these pathways; the HBx protein modulates viral replication and can influence the pathogenesis of the virus.
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文献 (33)
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PLoS pathogens 21:e1012800 PubMed39746094
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Virology journal 21:310 PubMed39609857
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JHEP reports : innovation in hepatology 6:101134 PubMed39386256
2024
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Polish journal of microbiology 73:217-235 PubMed38905278
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Journal of virology 98:e0150223 PubMed38315015
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Cellular and molecular gastroenterology and hepatology 17:219-235 PubMed37879404
2023
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Journal of virology 97:e0109023 PubMed37787533
2023
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Journal of virology 97:e0072223 PubMed37754761
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Microbiology spectrum :e0164123 PubMed37623314
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Viruses 15: PubMed37243280
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